ArticleDiagnostics (Basel, Switzerland)2022
Osteonecrosis of the Femoral Head: A Multidisciplinary Approach in Diagnostic Accuracy.
Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 18 citations in OpenAlex.
- A combined radiomics-clinical nomogram for assessing MRI-defined femoral Head collapse status in osteonecrosis of the femoral Head.Journal of applied clinical medical physics · 2026Article
- Osteoimmune microenvironmental failure in osteonecrosis of the femoral head: a necrosis-inflammation-repair loop and immune-editing-inspired framework for hip preservation.Frontiers in immunology · 2026Review
- Altered lineage commitment of bone marrow mesenchymal stem cells in idiopathic osteonecrosis of the femoral head.World journal of orthopedics · 2025Article
- Clinical, imaging, and histopathological characteristics of Vietnamese patients with late-stage avascular necrosis of the femoral head.BMC musculoskeletal disorders · 2025Article
- Total hip arthroplasty with tantalum rod extraction via direct anterior approach based on preoperative DCE-MRI and AI: a case report.Annals of medicine and surgery (2012) · 2025Article
- Clinical evaluation of blood flow in femoral head necrosis using color doppler ultrasound.Scientific reports · 2025Article
- Interpretable machine learning and radiomics in hip MRI diagnostics: comparing ONFH and OA predictions to experts.Frontiers in immunology · 2025Article
- To investigate the effect of neck-shaft angle in surgical hip dislocation combined with femoral neck rotational osteotomy in the treatment of osteonecrosis of the femoral head and to combine with finite element analysis.Frontiers in bioengineering and biotechnology · 2025Article
- Predicting steroid-induced osteonecrosis of the femoral head: role of lipid metabolism biomarkers and radiomics in young and middle-aged adults.Journal of orthopaedic surgery and research · 2024Article
- Comparison of SHD-IBG and PVIBGT in ONFH including mechanical and pathological analysis of failure cases.Scientific reports · 2024Article
- Editorial on Special Issue "Skeletal Radiology".Diagnostics (Basel, Switzerland) · 2023Article
- A Pilot Experiment to Measure the Initial Mechanical Stability of the Femoral Head Implant in a Cadaveric Model of Osteonecrosis of Femoral Head Involving up to 50% of the Remaining Femoral Head.Medicina (Kaunas, Lithuania) · 2023Article
- The Antagonism of Neuropeptide Y Type I Receptor (Y1R) Reserves the Viability of Bone Marrow Stromal Cells in the Milieu of Osteonecrosis of Femoral Head (ONFH).Biomedicines · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteonecrosis of the Femoral Head (ONFH) is a disabling disease affecting up to 30,000 people yearly in the United States alone. Diagnosis and staging of this pathology are both technically and logistically challenging, usually relying on imaging studies. Even anatomopathological studies, considered the gold standard for identifying ONFH, are not exempt from problems. In addition, the diagnosis is often made by different healthcare specialists, including orthopedic surgeons and radiologists, using different imaging modes, macroscopic features, and stages. Therefore, it is not infrequent to find disagreements between different specialists. The aim of this paper is to clarify the association and accuracy of ONFH diagnosis between healthcare professionals. To this end, femoral head specimens from patients with a diagnosis of ONFH were collected from patients undergoing hip replacement surgery. These samples were later histologically analyzed to establish an ONFH diagnosis. We found that clinico-radiological diagnosis of ONFH evidences a high degree of histological confirmation, thus showing an acceptable diagnostic accuracy. However, when the diagnoses of radiologists and orthopedic surgeons are compared with each other, there is only a moderate agreement. Our results underscore the need to develop an effective diagnosis based on a multidisciplinary approach to enhance currently limited accuracy and reliability.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.