Evidence map›Paper›PMID 35885590›Full record

ArticleDiagnostics (Basel, Switzerland)2022

DNA Methylation of HOXA11 Gene as Prognostic Molecular Marker in Human Gastric Adenocarcinoma.

Povilas Ignatavicius, Albertas Dauksa, Justas Zilinskas, Mintaute Kazokaite, Romualdas Riauka, Giedrius Barauskas

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Povilas IgnataviciusDepartment of Surgery, Medical Academy, Lithuanian University of Health Sciences, 50161 Kaunas, Lithuania.ORCID 0000-0002-6112-6235
Albertas DauksaDepartment of Surgery, Medical Academy, Lithuanian University of Health Sciences, 50161 Kaunas, Lithuania.
Justas ZilinskasDepartment of Surgery, Medical Academy, Lithuanian University of Health Sciences, 50161 Kaunas, Lithuania.
Mintaute KazokaiteInstitute of Endocrinology, Medical Academy, Lithuanian University of Health Sciences, 50161 Kaunas, Lithuania.ORCID 0000-0002-8202-5484
Romualdas RiaukaDepartment of Surgery, Medical Academy, Lithuanian University of Health Sciences, 50161 Kaunas, Lithuania.
Giedrius BarauskasDepartment of Surgery, Medical Academy, Lithuanian University of Health Sciences, 50161 Kaunas, Lithuania.
Lithuanian University of Health Sciences · LT

Funding

Lietuvos Mokslo Taryba S-MIP-17-80
6 · The paper itself

Abstract

Hypermethylation of tumor suppressor genes and hypomethylation of oncogenes might be identified as possible biomarkers in gastric cancer (GC). We aimed to assess the DNA methylation status of selected genes in GC tissue samples and evaluate these genes' prognostic importance on patient survival. Patients (99) diagnosed with GC and who underwent gastrectomy were included. We selected a group of genes (RAD51B, GFRA3, AKR7A3, HOXA11, TUSC3, FLI1, SEZ6L, GLDC, NDRG) which may be considered as potential tumor suppressor genes and oncogenes. Methylation of the HOXA11 gene promoter was significantly more frequent in GC tumor tissue (

Indexed as

gastric adenocarcinomaHOXA11methylationsurvival

Identifiers

PMID35885590
PMCPMC9317388
OpenAlexW4285035650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.