Evidence map›Paper›PMID 35885581›Full record

ArticleDiagnostics (Basel, Switzerland)2022

Prediction of Intraparenchymal Hemorrhage Progression and Neurologic Outcome in Traumatic Brain Injury Patients Using Radiomics Score and Clinical Parameters.

Yun-Ju Shih, Yan-Lin Liu, Jeon-Hor Chen, Chung-Han Ho, Cheng-Chun Yang, Tai-Yuan Chen, Te-Chang Wu, Ching-Chung Ko, Jonathan T Zhou, Yang Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  4. Review
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  10. Glibenclamide for Brain Contusions: Contextualizing a Promising Clinical Trial Design that Leverages an Imaging-Based TBI Endotype.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Yun-Ju ShihDepartment of Medical Imaging, Chi Mei Medical Center, Tainan 710, Taiwan.
Yan-Lin LiuDepartment of Radiological Sciences, University of California, Irvine, CA 92868, USA.ORCID 0000-0003-4912-1746
Jeon-Hor ChenDepartment of Radiological Sciences, University of California, Irvine, CA 92868, USA.
Chung-Han HoDepartment of Medical Research, Chi Mei Medical Center, Tainan 710, Taiwan.ORCID 0000-0001-5925-8477
Cheng-Chun YangDepartment of Medical Imaging, Chi Mei Medical Center, Tainan 710, Taiwan.ORCID 0000-0002-1124-8154
Tai-Yuan ChenDepartment of Medical Imaging, Chi Mei Medical Center, Tainan 710, Taiwan.
Te-Chang WuDepartment of Medical Imaging, Chi Mei Medical Center, Tainan 710, Taiwan.ORCID 0000-0002-4408-4264
Ching-Chung KoDepartment of Medical Imaging, Chi Mei Medical Center, Tainan 710, Taiwan.
Jonathan T ZhouDepartment of Radiological Sciences, University of California, Irvine, CA 92868, USA.
Yang ZhangDepartment of Radiological Sciences, University of California, Irvine, CA 92868, USA.
Min-Ying SuDepartment of Radiological Sciences, University of California, Irvine, CA 92868, USA.ORCID 0000-0002-3069-0271
Chi Mei Medical Center · TWUniversity of California, Irvine · USKaohsiung Medical University · TWRutgers, The State University of New Jersey · US

Funding

University of California Health Participation in the National COVID Cohort Collaborative (N3C)UL1TR001414 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, VILAIN, ERIC J. · 2015 to 2023
$35.1M
NCATS NIH HHS UL1 TR001414
6 · The paper itself

Abstract

(1) Background: Radiomics analysis of spontaneous intracerebral hemorrhages on computed tomography (CT) images has been proven effective in predicting hematoma expansion and poor neurologic outcome. In contrast, there is limited evidence on its predictive abilities for traumatic intraparenchymal hemorrhage (IPH). (2) Methods: A retrospective analysis of 107 traumatic IPH patients was conducted. Among them, 45 patients (42.1%) showed hemorrhagic progression of contusion (HPC) and 51 patients (47.7%) had poor neurological outcome. The IPH on the initial CT was manually segmented for radiomics analysis. After feature extraction, selection and repeatability evaluation, several machine learning algorithms were used to derive radiomics scores (R-scores) for the prediction of HPC and poor neurologic outcome. (3) Results: The AUCs for R-scores alone to predict HPC and poor neurologic outcome were 0.76 and 0.81, respectively. Clinical parameters were used to build comparison models. For HPC prediction, variables including age, multiple IPH, subdural hemorrhage, Injury Severity Score (ISS), international normalized ratio (INR) and IPH volume taken together yielded an AUC of 0.74, which was significantly (

Indexed as

brain injuriescerebral hemorrhagecontusionsmachine learningradiomicstomographytraumaticX-ray computed

Identifiers

PMID35885581
PMCPMC9320220
OpenAlexW4285007561

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.