Evidence map›Paper›PMID 35885562›Full record

ReviewDiagnostics (Basel, Switzerland)2022

Cytogenetic and Genetic Abnormalities with Diagnostic Value in Myelodysplastic Syndromes (MDS): Focus on the Pre-Messenger RNA Splicing Process.

Nathalie Douet-Guilbert, Benoît Soubise, Delphine G Bernard, Marie-Bérengère Troadec

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nathalie Douet-GuilbertUniversité de Brest, Inserm, EFS, UMR 1078, GGB, F-29200 Brest, France.
Benoît SoubiseUniversité de Brest, Inserm, EFS, UMR 1078, GGB, F-29200 Brest, France.ORCID 0000-0002-9062-8285
Delphine G BernardUniversité de Brest, Inserm, EFS, UMR 1078, GGB, F-29200 Brest, France.ORCID 0000-0002-9439-5482
Marie-Bérengère TroadecUniversité de Brest, Inserm, EFS, UMR 1078, GGB, F-29200 Brest, France.ORCID 0000-0003-2668-9670
Inserm · FR

Funding

Association connaître et combattre la myélodysplasie 2020-2022Association Fondation de l'Avenir 2021-2023Association Gaétan Saleün 2020-2022Association Halte au Cancer 2021-2022fonds INNOVEO Brest 2021-2023le Collectif Agora de Guilers 2021-2022Ligue Régionale contre le cancer (comités 16, 22, 29, 35, 56, 41 and 85) comités 16, 22, 29, 35, 56, 41 and 85
6 · The paper itself

Abstract

Myelodysplastic syndromes (MDS) are considered to be diseases associated with splicing defects. A large number of genes involved in the pre-messenger RNA splicing process are mutated in MDS. Deletion of 5q and 7q are of diagnostic value, and those chromosome regions bear the numbers of splicing genes potentially deleted in del(5q) and del(7q)/-7 MDS. In this review, we present the splicing genes already known or suspected to be implicated in MDS pathogenesis. First, we focus on the splicing genes located on chromosome 5 (

Indexed as

chromosome abnormalitiesdel(5q)diagnosisLUC7L2myelodysplasiaPRPF8RBM22SF3B1SLU7splicingU2AF1

Identifiers

PMID35885562
PMCPMC9320363
OpenAlexW4284884327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.