Evidence map›Paper›PMID 35885521›Full record

ReviewDiagnostics (Basel, Switzerland)2022

The Use of Confocal Laser Endomicroscopy in Diagnosing Barrett's Esophagus and Esophageal Adenocarcinoma.

Jitka Vaculová, Radek Kroupa, Zdeněk Kala, Jiří Dolina, Tomáš Grolich, Jakub Vlažný, David Said, Lydie Izakovičová Hollá, Petra Bořilová Linhartová, Vladimír Procházka and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Probe-based confocal laser endomicroscopy for optical biopsy of basal cell carcinoma of the auricle.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2026
    Article
  2. Article
  3. Optical biopsy of nasal cavity cancer with confocal laser endomicroscopy - a pilot study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Quantitative imaging in medicine and surgery · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Jitka VaculováDepartment of Gastroenterology and Internal Medicine, University Hospital Brno, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic.ORCID 0000-0002-7998-772X
Radek KroupaDepartment of Gastroenterology and Internal Medicine, University Hospital Brno, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic.ORCID 0000-0003-2315-8305
Zdeněk KalaDepartment of Surgery, University Hospital Brno, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic.ORCID 0000-0003-4187-388X
Jiří DolinaDepartment of Gastroenterology and Internal Medicine, University Hospital Brno, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic.ORCID 0000-0002-9061-5273
Tomáš GrolichDepartment of Surgery, University Hospital Brno, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic.
Jakub VlažnýDepartment of Pathology, University Hospital Brno, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic.
David SaidDepartment of Pathology, University Hospital Brno, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic.
Lydie Izakovičová HolláDepartment of Pathophysiology, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic.ORCID 0000-0002-7610-8929
Petra Bořilová LinhartováDepartment of Pathophysiology, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic.ORCID 0000-0003-0953-3615
Vladimír ProcházkaDepartment of Surgery, University Hospital Brno, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic.
Marek JoukalDepartment of Anatomy, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic.ORCID 0000-0002-7013-1693
Petr JabandžievDepartment of Pediatrics, University Hospital Brno, Faculty of Medicine, Masaryk University, 61300 Brno, Czech Republic.ORCID 0000-0002-4094-2364
Ondřej SlabýCentral European Institute of Technology, Masaryk University, 62500 Brno, Czech Republic.ORCID 0000-0002-8450-0584
Lumír KunovskýDepartment of Surgery, University Hospital Brno, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic.ORCID 0000-0003-2985-8759
Masaryk University · CZCentral European Institute of Technology · CZ

Funding

Ministry of Health of the Czech Republic NU20-03-00126the Ministry of Health, Czech Republic - conceptual development of research organization FNBr, 65269705the Ministry of Health, Czech Republic - conceptual development of research organization FNBr, 65269705, Sup 3/21
6 · The paper itself

Abstract

Confocal laser endomicroscopy (CLE) is a diagnostic technique that enables real-time microscopic imaging during microscopic examination and evaluation of epithelial structures with 1000-fold magnification. CLE can be used in the diagnosis of various pathologies, in pneumology, and in urology, and it is very widely utilized in gastroenterology, most importantly in the diagnosis of Barrett's esophagus (BE), esophageal adenocarcinoma (EAC), biliary strictures, and cystic pancreatic lesions. A literature search was made in MEDLINE/PubMed and Google Scholar databases while focusing on diagnostics using CLE of BE and EAC. We then examined randomized and observational studies, systematic reviews, and meta-analyses relating to the utilization of CLE in BE and EAC diagnostics. Here, we discuss whether CLE can be a suitable diagnostic method for surveillance of BE. Even though many studies have proven that CLE increases diagnostic accuracy in detecting neoplastic transformation of BE, CLE is still not used as a standard diagnostic tool in BE surveillance due to a deficiency of scientific evidence. More studies and data are needed if CLE is to find a place as a new technique in BE surveillance.

Indexed as

Barrett’s esophagusconfocal laser endomicroscopydiagnosisearly esophageal adenocarcinomaesophageal cancerprobe-based confocal laser endomicroscopy

Identifiers

PMID35885521
PMCPMC9317308
OpenAlexW4283771010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.