Evidence map›Paper›PMID 35885513›Full record

ArticleDiagnostics (Basel, Switzerland)2022

AI-Based Chest CT Analysis for Rapid COVID-19 Diagnosis and Prognosis: A Practical Tool to Flag High-Risk Patients and Lower Healthcare Costs.

Giovanni Esposito, Benoit Ernst, Monique Henket, Marie Winandy, Avishek Chatterjee, Simon Van Eyndhoven, Jelle Praet, Dirk Smeets, Paul Meunier, Renaud Louis and 2 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Giovanni EspositoIcometrix, 3012 Leuven, Belgium.
Benoit ErnstPneumology Department, University of Liège, 4000 Liège, Belgium.ORCID 0000-0002-1096-049X
Monique HenketRespiratory Medicine Department, University Hospital of Liège, 4000 Liège, Belgium.
Marie WinandyRespiratory Medicine Department, University Hospital of Liège, 4000 Liège, Belgium.ORCID 0000-0003-1739-0677
Avishek ChatterjeeIcometrix, 3012 Leuven, Belgium.
Simon Van EyndhovenIcometrix, 3012 Leuven, Belgium.ORCID 0000-0003-0752-4969
Jelle PraetIcometrix, 3012 Leuven, Belgium.
Dirk SmeetsIcometrix, 3012 Leuven, Belgium.
Paul MeunierRadiology Department, University Hospital of Liège, 4000 Liège, Belgium.
Renaud LouisRespiratory Medicine Department, University Hospital of Liège, 4000 Liège, Belgium.
Philippe KolhInformation Systems Management Department, University Hospital of Liège, 4000 Liège, Belgium.
Julien GuiotRespiratory Medicine Department, University Hospital of Liège, 4000 Liège, Belgium.ORCID 0000-0001-7800-1730
University of Liège · BEIcometrix (Belgium) · BE

Funding

European Union iCOVID - 101016131
6 · The paper itself

Abstract

Early diagnosis of COVID-19 is required to provide the best treatment to our patients, to prevent the epidemic from spreading in the community, and to reduce costs associated with the aggravation of the disease. We developed a decision tree model to evaluate the impact of using an artificial intelligence-based chest computed tomography (CT) analysis software (icolung, icometrix) to analyze CT scans for the detection and prognosis of COVID-19 cases. The model compared routine practice where patients receiving a chest CT scan were not screened for COVID-19, with a scenario where icolung was introduced to enable COVID-19 diagnosis. The primary outcome was to evaluate the impact of icolung on the transmission of COVID-19 infection, and the secondary outcome was the in-hospital length of stay. Using EUR 20000 as a willingness-to-pay threshold, icolung is cost-effective in reducing the risk of transmission, with a low prevalence of COVID-19 infections. Concerning the hospitalization cost, icolung is cost-effective at a higher value of COVID-19 prevalence and risk of hospitalization. This model provides a framework for the evaluation of AI-based tools for the early detection of COVID-19 cases. It allows for making decisions regarding their implementation in routine practice, considering both costs and effects.

Indexed as

AI-based CT-scan analysisCOVIDCOVID-19 infection spread preventionhospital days reductionincremental cost-effectiveness ratioinfection reductionpatient flow managementPCR test rationalizationSARS-CoV-2

Identifiers

PMID35885513
PMCPMC9324628
OpenAlexW4283764266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.