Evidence map›Paper›PMID 35885422›Full record

ArticleDiagnostics (Basel, Switzerland)2022

A Radiation-Free Classification Pipeline for Craniosynostosis Using Statistical Shape Modeling.

Matthias Schaufelberger, Reinald Kühle, Andreas Wachter, Frederic Weichel, Niclas Hagen, Friedemann Ringwald, Urs Eisenmann, Jürgen Hoffmann, Michael Engel, Christian Freudlsperger and 1 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Machine learning applications in craniosynostosis diagnosis and treatment prediction: a systematic review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Pooled it
  2. Quantifying Sagittal Craniosynostosis Severity: A Machine Learning Approach With CranioRate.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Mesh2SSM: From Surface Meshes to Statistical Shape Models of Anatomy.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2023
    Article
  8. Article
  9. Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Matthias SchaufelbergerInstitute of Biomedical Engineering (IBT), Karlsruhe Institute of Technology (KIT), Kaiserstr. 12, 76131 Karlsruhe, Germany.ORCID 0000-0001-7501-9222
Reinald KühleDepartment of Oral, Dental and Maxillofacial Diseases, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.ORCID 0000-0002-9941-6772
Andreas WachterInstitute of Biomedical Engineering (IBT), Karlsruhe Institute of Technology (KIT), Kaiserstr. 12, 76131 Karlsruhe, Germany.ORCID 0000-0002-2868-6492
Frederic WeichelDepartment of Oral, Dental and Maxillofacial Diseases, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.ORCID 0000-0002-0222-7060
Niclas HagenInstitute of Medical Informatics, Heidelberg University Hospital, Im Neuenheimer Feld 130.3, 69120 Heidelberg, Germany.ORCID 0000-0001-8578-8703
Friedemann RingwaldInstitute of Medical Informatics, Heidelberg University Hospital, Im Neuenheimer Feld 130.3, 69120 Heidelberg, Germany.ORCID 0000-0002-0572-4820
Urs EisenmannInstitute of Medical Informatics, Heidelberg University Hospital, Im Neuenheimer Feld 130.3, 69120 Heidelberg, Germany.
Jürgen HoffmannDepartment of Oral, Dental and Maxillofacial Diseases, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.ORCID 0000-0002-1322-755X
Michael EngelDepartment of Oral, Dental and Maxillofacial Diseases, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.
Christian FreudlspergerDepartment of Oral, Dental and Maxillofacial Diseases, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany.ORCID 0000-0002-4289-0457
Werner NahmInstitute of Biomedical Engineering (IBT), Karlsruhe Institute of Technology (KIT), Kaiserstr. 12, 76131 Karlsruhe, Germany.ORCID 0000-0001-8095-5090
Heidelberg University · DEKarlsruhe Institute of Technology · DE

Funding

HEiKA Strategic Partnership HEiKA_19-17
6 · The paper itself

Abstract

backgroundCraniosynostosis is a condition caused by the premature fusion of skull sutures, leading to irregular growth patterns of the head. Three-dimensional photogrammetry is a radiation-free alternative to the diagnosis using computed tomography. While statistical shape models have been proposed to quantify head shape, no shape-model-based classification approach has been presented yet.

methodsWe present a classification pipeline that enables an automated diagnosis of three types of craniosynostosis. The pipeline is based on a statistical shape model built from photogrammetric surface scans. We made the model and pathology-specific submodels publicly available, making it the first publicly available craniosynostosis-related head model, as well as the first focusing on infants younger than 1.5 years. To the best of our knowledge, we performed the largest classification study for craniosynostosis to date.

resultsOur classification approach yields an accuracy of 97.8 %, comparable to other state-of-the-art methods using both computed tomography scans and stereophotogrammetry. Regarding the statistical shape model, we demonstrate that our model performs similar to other statistical shape models of the human head.

conclusionWe present a state-of-the-art shape-model-based classification approach for a radiation-free diagnosis of craniosynostosis. Our publicly available shape model enables the assessment of craniosynostosis on realistic and synthetic data.

Indexed as

classificationcraniosynostosismachine learningshape analysisstatistical shape modelstereophotogrammetrytemplate morphing

Identifiers

PMID35885422
PMCPMC9323148
OpenAlexW4283271501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.