Evidence map›Paper›PMID 35885066›Full record

ArticleBiomedicines2022

Hyperreactivity of Salivary Alpha-Amylase to Acute Psychosocial Stress and Norepinephrine Infusion in Essential Hypertension.

Lisa-Marie Walther, Roland von Känel, Claudia Zuccarella-Hackl, Petra H Wirtz

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Lisa-Marie WaltherBiological Work and Health Psychology, Department of Psychology, University of Konstanz, 78464 Konstanz, Germany.ORCID 0000-0001-5981-1412
Roland von KänelDepartment of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.ORCID 0000-0002-8929-5129
Claudia Zuccarella-HacklDepartment of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Petra H WirtzBiological Work and Health Psychology, Department of Psychology, University of Konstanz, 78464 Konstanz, Germany.ORCID 0000-0002-4897-1645
University of Konstanz · DEUniversity of Zurich · CH

Funding

Deutsche Forschungsgemeinschaft EXC 2117-422037984Deutsche Forschungsgemeinschaft INST 38/550-1Inselspital Bern F3-1395Swiss National Science Foundation 320030_122406Swiss National Science Foundation PP00P1_128565/1University of Zurich Research Grant 2003
6 · The paper itself

Abstract

It is unknown whether the observed general physiological hyperreactivity to acute psychosocial stress in essential hypertension also extends to salivary alpha-amylase (sAA), a surrogate sympathetic nervous system marker. Here, we investigated sAA reactivity to acute psychosocial stress in essential hypertensive males (HT) as compared to normotensive controls (NT). To shed light on underlying mechanisms, we moreover tested for sAA reactivity following a standardized norepinephrine (NE) infusion. We hypothesized that both acute psychosocial stress and an NE infusion of similar duration would lead to greater sAA reactivity in HT than in NT. In the

Indexed as

acute psychosocial stressessential hypertensionnorepinephrine infusionphysiological hyperreactivitysalivary alpha-amylaseTrier Social Stress Test

Identifiers

PMID35885066
PMCPMC9312828
OpenAlexW4286494103

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.