Evidence map›Paper›PMID 35884866›Full record

ArticleBiomedicines2022

APOE ε4 in Depression-Associated Memory Impairment-Evidence from Genetic and MicroRNA Analyses.

Sarah Bonk, Kevin Kirchner, Sabine Ameling, Linda Garvert, Henry Völzke, Matthias Nauck, Uwe Völker, Hans J Grabe, Sandra Van der Auwera

Open access · goldAbstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Cardiovascular disease and depression: a narrative review.Frontiers in cardiovascular medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sarah BonkDepartment of Psychiatry and Psychotherapy, University Medicine Greifswald, 17489 Greifswald, Germany.
Kevin KirchnerDepartment of Psychiatry and Psychotherapy, University Medicine Greifswald, 17489 Greifswald, Germany.
Sabine AmelingInterfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17475 Greifswald, Germany.
Linda GarvertDepartment of Psychiatry and Psychotherapy, University Medicine Greifswald, 17489 Greifswald, Germany.
Henry VölzkeGerman Centre for Cardiovascular Research (DZHK), Partner Site Greifswald, 17475 Greifswald, Germany.
Matthias NauckGerman Centre for Cardiovascular Research (DZHK), Partner Site Greifswald, 17475 Greifswald, Germany.ORCID 0000-0002-6678-7964
Uwe VölkerInterfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17475 Greifswald, Germany.
Hans J GrabeDepartment of Psychiatry and Psychotherapy, University Medicine Greifswald, 17489 Greifswald, Germany.ORCID 0000-0003-3684-4208
Sandra Van der AuweraDepartment of Psychiatry and Psychotherapy, University Medicine Greifswald, 17489 Greifswald, Germany.ORCID 0000-0002-1757-7768
Universitätsmedizin Greifswald · DE

Funding

Deutsche Forschungsgemeinschaft 403694598Federal Ministry of Education and Research 01KU2004, 03ZIK012, 01ZZ9603, 01ZZ0103, 01ZZ0403
6 · The paper itself

Abstract

(1) Background: The aim of this study was to replicate a reported interaction between APOE ε4 status and depression on memory function in two independent, nondemented samples from the general population and to examine the potential role of circulating plasma miRNAs. (2) Methods: The impact of the APOE ε4 allele on verbal memory and the interaction with depression is investigated in two large general-population cohorts from the Study of Health in Pomerania (SHIP, total

Indexed as

Alzheimer’s diseaseamyloid betaAPOE ε4cognitiondepressionMDDmemorymiRNA

Identifiers

PMID35884866
PMCPMC9313258
OpenAlexW4283741048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.