Evidence map›Paper›PMID 35884856›Full record

ArticleBiomedicines2022

Magnetoliposomes Containing Multicore Nanoparticles and a New Antitumor Thienopyridine Compound with Potential Application in Chemo/Thermotherapy.

Fábio A C Lopes, André V F Fernandes, Juliana M Rodrigues, Maria-João R P Queiroz, Bernardo G Almeida, Ana Pires, André M Pereira, João P Araújo, Elisabete M S Castanheira, Ana Rita O Rodrigues and 1 more

Abstract read
In one paragraph

Article in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fábio A C LopesPhysics Centre of Minho and Porto Universities (CF-UM-UP), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
André V F FernandesPhysics Centre of Minho and Porto Universities (CF-UM-UP), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
Juliana M RodriguesCentre of Chemistry (CQUM), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
Maria-João R P QueirozCentre of Chemistry (CQUM), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0002-4322-8035
Bernardo G AlmeidaPhysics Centre of Minho and Porto Universities (CF-UM-UP), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
Ana PiresLaPMET (Laboratory of Physics for Materials and Emergent Technologies), Associate Laboratory, 4710-057 Braga, Portugal.
André M PereiraLaPMET (Laboratory of Physics for Materials and Emergent Technologies), Associate Laboratory, 4710-057 Braga, Portugal.
João P AraújoLaPMET (Laboratory of Physics for Materials and Emergent Technologies), Associate Laboratory, 4710-057 Braga, Portugal.ORCID 0000-0002-1646-7727
Elisabete M S CastanheiraPhysics Centre of Minho and Porto Universities (CF-UM-UP), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0002-5829-6081
Ana Rita O RodriguesPhysics Centre of Minho and Porto Universities (CF-UM-UP), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0002-6094-1713
Paulo J G CoutinhoPhysics Centre of Minho and Porto Universities (CF-UM-UP), University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.ORCID 0000-0003-4426-9207

Funding

Compete2020 POCI-01-0145-FEDER-028020European Social Fund-North Portugal Regional Operational Program SFRH/BD/115844/2016Fundação para a Ciência e Tecnologia PTDC/QUI-QFI/28020/2017Fundação para a Ciência e Tecnologia SFRH/BD/115844/2016Fundação para a Ciência e Tecnologia UIDB/04650/2020
6 · The paper itself

Abstract

Multicore magnetic nanoparticles of manganese ferrite were prepared using carboxymethyl dextran as an agglutinating compound or by an innovative method using melamine as a cross-coupling agent. The nanoparticles prepared using melamine exhibited a flower-shape structure, a saturation magnetization of 6.16 emu/g and good capabilities for magnetic hyperthermia, with a specific absorption rate (SAR) of 0.14 W/g. Magnetoliposome-like structures containing the multicore nanoparticles were prepared, and their bilayer structure was confirmed by FRET (Förster Resonance Energy Transfer) assays. The nanosystems exhibited sizes in the range of 250-400 nm and a low polydispersity index. A new antitumor thienopyridine derivative, 7-[4-(pyridin-2-yl)-1

Indexed as

antitumor thienopyridine derivativechemotherapymagnetic hyperthermiamagnetoliposomesmulticore magnetic nanoparticles

Identifiers

PMID35884856
PMCPMC9313298

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.