Evidence map›Paper›PMID 35884788›Full record

ReviewBiomedicines2022

What We Have Learned from Animal Models to Understand the Etiology and Pathology of Endometrioma-Related Infertility.

Zhouyurong Tan, Sze-Wan Hung, Xu Zheng, Chi-Chiu Wang, Jacqueline Pui-Wah Chung, Tao Zhang

Abstract readReview
In one paragraph

Review in Biomedicines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhouyurong TanDepartment of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong.ORCID 0000-0002-5446-2273
Sze-Wan HungDepartment of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong.ORCID 0000-0003-0576-4707
Xu ZhengDepartment of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong.
Chi-Chiu WangDepartment of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong.ORCID 0000-0002-3928-7278
Jacqueline Pui-Wah ChungDepartment of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong.
Tao ZhangDepartment of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometrioma (OMA) is the most common subtype of endometriosis, in which the endometriotic lesions are implanted in the ovary. Women with OMA are usually associated with infertility, presenting with reduced ovarian reserve, low oocyte quantity and quality, and poor fertility outcomes. However, the underlying pathological mechanisms in OMA-related infertility are still unclear. Due to the limitations and ethical issues of human studies in reproduction, animal models that recapitulate OMA characteristics and its related infertility are critical for mechanistic studies and subsequent drug development, preclinical testing, and clinical trials. This review summarized the investigations of OMA-related infertility based on previous and latest endometrioma models, providing the possible pathogenesis and potential therapeutic targets for further studies.

Indexed as

endometriomainfertilitymodelspathophysiologytherapeutic targets

Identifiers

PMID35884788
PMCPMC9313443

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.