Evidence map›Paper›PMID 35884595›Full record

ArticleCancers2022

The "Balloon-Like" Sign: Differential Diagnosis between Postoperative Air Leak and Residual Pleural Space: Radiological Findings and Clinical Implications of the Young-Laplace Equation.

Francesco Petrella, Stefania Rizzo, Luca Bertolaccini, Monica Casiraghi, Lara Girelli, Giorgio Lo Iacono, Antonio Mazzella, Lorenzo Spaggiari

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Francesco PetrellaDepartment of Thoracic Surgery, IEO European Institute of Oncology, IRCCS, 20141 Milan, Italy.ORCID 0000-0001-5945-1576
Stefania RizzoDepartment of Radiology, Ente Ospedaliero Cantonale (EOC) Istituto di Imaging della Svizzera Italiana (IIMSI), 6903 Lugano, Switzerland.ORCID 0000-0002-5151-0866
Luca BertolacciniDepartment of Thoracic Surgery, IEO European Institute of Oncology, IRCCS, 20141 Milan, Italy.ORCID 0000-0002-1153-3334
Monica CasiraghiDepartment of Thoracic Surgery, IEO European Institute of Oncology, IRCCS, 20141 Milan, Italy.ORCID 0000-0001-5986-7811
Lara GirelliDepartment of Thoracic Surgery, IEO European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Giorgio Lo IaconoDepartment of Thoracic Surgery, IEO European Institute of Oncology, IRCCS, 20141 Milan, Italy.ORCID 0000-0003-2629-7781
Antonio MazzellaDepartment of Thoracic Surgery, IEO European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Lorenzo SpaggiariDepartment of Thoracic Surgery, IEO European Institute of Oncology, IRCCS, 20141 Milan, Italy.
Istituti di Ricovero e Cura a Carattere Scientifico · ITUniversity of Milan · ITEnte Ospedaliero Cantonale · CH

Funding

Italian Ministry of Health "Ricerca Corrente", "5 × 1000" funds.Italian Ministry of Health with "Ricerca Corrente", "5 × 1000" funds. "5 × 1000" funds.
6 · The paper itself

Abstract

In this paper, we propose a radiological sign for an appropriate differential diagnosis between postoperative pleural space and active air leak after lung resection. In the case of residual pleural space without any active air leak, the lung takes the form of a round balloon due to the hyperinflation condition, which is governed by the Young-Laplace equation describing the capillary pressure difference sustained across the interface between two static fluids, such as water and air, due to the phenomenon of wall tension. The two principal mechanisms by which a lung forms a spherical image are shear-controlled detachment induced by shear stress on the membrane surface, and spontaneous detachment induced by a gradient in Young-Laplace pressure. On the contrary, the lung maintains its tapered shape in the case of an active air leak because the continuous air refill does not allow a complete parenchyma re-expansion.

Indexed as

postoperative air leaksresidual pleural spaceYoung–Laplace equation

Identifiers

PMID35884595
PMCPMC9317249
OpenAlexW4286005598

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.