Evidence map›Paper›PMID 35884473›Full record

ArticleCancers2022

Disparities in Metabolic Conditions and Cancer Characteristics among Hispanic Women with Breast Cancer: A Multi-Institutional Study.

Iktej S Jabbal, Alok Dwivedi, Nadeem Bilani, Barbara Dominguez, Gehan Botrus, Zeina Nahleh

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Iktej S JabbalDepartment of Hematology & Oncology, Maroone Cancer Center, Cleveland Clinic, Weston, FL 33331, USA.ORCID 0000-0001-8991-7445
Alok DwivediDepartment of Molecular and Translational Medicine, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA.
Nadeem BilaniDepartment of Internal Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Barbara DominguezDepartment of Hematology & Oncology, Maroone Cancer Center, Cleveland Clinic, Weston, FL 33331, USA.ORCID 0000-0001-7618-4545
Gehan BotrusDepartment of Hematology & Oncology, Mayo Clinic in Arizona, Phoenix, AZ 85054, USA.
Zeina NahlehDepartment of Hematology & Oncology, Maroone Cancer Center, Cleveland Clinic, Weston, FL 33331, USA.
Cleveland Clinic Florida · USIcahn School of Medicine at Mount Sinai · USMayo Clinic Hospital · USTexas Tech University · US

Funding

Maroone Cancer Center, Cleveland Clinic Florida NA
6 · The paper itself

Abstract

While the associations of common metabolic conditions with ethnicity have been previously described, disparity among Hispanic individuals based on country of origin is understudied. This multi-institutional analysis explored the prevalence of metabolic conditions and their association with cancer subtypes among Mexican and non-Mexican Hispanics. After IRB approval, we conducted a cross-sectional study at two academic medical centers with a significant Hispanic patient population (Texas Tech University Health Sciences Center, El Paso, TX (TTUHSC-EP) and Cleveland Clinic Florida in Weston, FL (CCF)). A total of n = 1020 self-identified Hispanic patients with breast cancer consecutively diagnosed between 2005 and 2014 were selected from the two institutional databases. Comparisons between Mexican and Non-Mexican Hispanics revealed variations in tumor types and metabolic conditions. Mexican Hispanics were found to have a higher prevalence of diabetes mellitus (27.8% vs. 14.2%, p < 0.001), obesity (51.0% vs. 32.5%, p < 0.001), and ductal carcinoma type (86.6 vs. 73.4%, p < 0.001). On the other hand, hormone-receptor-positive breast cancer was more common in non-Mexicans, while Mexicans had more triple-negative breast cancer, especially in premenopausal women. In addition to highlighting these variations among Hispanic patients with breast cancer, this study supports a more focused approach to addressing obesity and other metabolic conditions prevalent in the Hispanic population with breast cancer. Moreover, Hispanic individuals with breast cancer are diverse and should not be lumped under one category without reference to their country of origin regarding the impact of race and ethnicity.

Indexed as

breast cancerHispanic ethnicitymetabolic abnormalities

Identifiers

PMID35884473
PMCPMC9317401
OpenAlexW4285595018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.