Evidence map›Paper›PMID 35884424›Full record

ArticleCancers2022

Isolation of Circulating Tumor Cells from Seminal Fluid of Patients with Prostate Cancer Using Inertial Microfluidics.

Alexey S Rzhevskiy, Alina Y Kapitannikova, Steven A Vasilescu, Tamilla A Karashaeva, Sajad Razavi Bazaz, Mark S Taratkin, Dmitry V Enikeev, Vladimir Y Lekarev, Evgeniy V Shpot, Denis V Butnaru and 4 more

Abstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Technologies for Viable Circulating Tumor Cell Isolation.International journal of molecular sciences · 2022
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alexey S RzhevskiyInstitute of Molecular Theranostics, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.ORCID 0000-0002-4042-7813
Alina Y KapitannikovaInstitute of Molecular Theranostics, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Steven A VasilescuSchool of Biomedical Engineering, University of Technology Sydney, Sydney 2007, Australia.
Tamilla A KarashaevaInstitute of Molecular Theranostics, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.ORCID 0000-0002-4747-4102
Sajad Razavi BazazSchool of Biomedical Engineering, University of Technology Sydney, Sydney 2007, Australia.ORCID 0000-0002-6419-3361
Mark S TaratkinInstitute for Urology and Reproductive Health, Sechenov University, 119146 Moscow, Russia.
Dmitry V EnikeevInstitute for Urology and Reproductive Health, Sechenov University, 119146 Moscow, Russia.ORCID 0000-0001-7169-2209
Vladimir Y LekarevInstitute for Urology and Reproductive Health, Sechenov University, 119146 Moscow, Russia.
Evgeniy V ShpotInstitute for Urology and Reproductive Health, Sechenov University, 119146 Moscow, Russia.
Denis V ButnaruInstitute for Urology and Reproductive Health, Sechenov University, 119146 Moscow, Russia.
Sergey M DeyevInstitute of Molecular Theranostics, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.ORCID 0000-0002-3952-0631
Jean Paul ThieryInstitute of Molecular Theranostics, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.
Andrei V ZvyaginInstitute of Molecular Theranostics, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.ORCID 0000-0001-8799-2257
Majid Ebrahimi WarkianiInstitute of Molecular Theranostics, Sechenov First Moscow State Medical University, 119991 Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer (PCa) diagnosis is primarily based on prostate-specific antigen (PSA) testing and prostate tissue biopsies. However, PSA testing has relatively low specificity, while tissue biopsies are highly invasive and have relatively low sensitivity at early stages of PCa. As an alternative, we developed a technique of liquid biopsy, based on isolation of circulating tumor cells (CTCs) from seminal fluid (SF). The recovery of PCa cells from SF was demonstrated using PCa cell lines, achieving an efficiency and throughput as high as 89% (±3.8%) and 1.7 mL min

Indexed as

circulating tumor cellsliquid biopsymicrofluidicsprostate cancerseminal fluid

Identifiers

PMID35884424
PMCPMC9318520

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.