Evidence map›Paper›PMID 35884418›Full record

ReviewCancers2022

Artificial Intelligence for Thyroid Nodule Characterization: Where Are We Standing?

Salvatore Sorrenti, Vincenzo Dolcetti, Maija Radzina, Maria Irene Bellini, Fabrizio Frezza, Khushboo Munir, Giorgio Grani, Cosimo Durante, Vito D'Andrea, Emanuele David and 3 more

Abstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Salvatore SorrentiDepartment of Surgical Sciences, "Sapienza" University of Rome, 00161 Rome, Italy.ORCID 0000-0003-0427-6648
Vincenzo DolcettiDepartment of Radiological, Anatomo-Pathological Sciences, "Sapienza" University of Rome, 00161 Rome, Italy.ORCID 0000-0001-8397-8343
Maija RadzinaRadiology Research Laboratory, Riga Stradins University, LV-1007 Riga, Latvia.ORCID 0000-0002-9518-4855
Maria Irene BelliniDepartment of Surgical Sciences, "Sapienza" University of Rome, 00161 Rome, Italy.ORCID 0000-0003-0730-4923
Fabrizio FrezzaDepartment of Information Engineering, Electronics and Telecommunications, "Sapienza" University of Rome, 00184 Rome, Italy.ORCID 0000-0001-9457-7617
Khushboo MunirDepartment of Information Engineering, Electronics and Telecommunications, "Sapienza" University of Rome, 00184 Rome, Italy.ORCID 0000-0002-4867-5707
Giorgio GraniDepartment of Translational and Precision Medicine, "Sapienza" University of Rome, 00161 Rome, Italy.ORCID 0000-0002-0388-1283
Cosimo DuranteDepartment of Translational and Precision Medicine, "Sapienza" University of Rome, 00161 Rome, Italy.ORCID 0000-0002-1791-5915
Vito D'AndreaDepartment of Surgical Sciences, "Sapienza" University of Rome, 00161 Rome, Italy.ORCID 0000-0001-5709-2530
Emanuele DavidDepartment of Translational and Precision Medicine, "Sapienza" University of Rome, 00161 Rome, Italy.
Pietro Giorgio CalòDepartment of Surgical Sciences, "Policlinico Universitario Duilio Casula", University of Cagliari, 09042 Monserrato, Italy.ORCID 0000-0001-9637-1145
Eleonora LoriDepartment of Surgical Sciences, "Sapienza" University of Rome, 00161 Rome, Italy.ORCID 0000-0003-1943-4952
Vito CantisaniDepartment of Radiological, Anatomo-Pathological Sciences, "Sapienza" University of Rome, 00161 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Machine learning (ML) is an interdisciplinary sector in the subset of artificial intelligence (AI) that creates systems to set up logical connections using algorithms, and thus offers predictions for complex data analysis. In the present review, an up-to-date summary of the current state of the art regarding ML and AI implementation for thyroid nodule ultrasound characterization and cancer is provided, highlighting controversies over AI application as well as possible benefits of ML, such as, for example, training purposes. There is evidence that AI increases diagnostic accuracy and significantly limits inter-observer variability by using standardized mathematical algorithms. It could also be of aid in practice settings with limited sub-specialty expertise, offering a second opinion by means of radiomics and computer-assisted diagnosis. The introduction of AI represents a revolutionary event in thyroid nodule evaluation, but key issues for further implementation include integration with radiologist expertise, impact on workflow and efficiency, and performance monitoring.

Indexed as

artificial intelligencemachine learningthyroid cancer

Identifiers

PMID35884418
PMCPMC9315681

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.