Evidence map›Paper›PMID 35884348›Full record

ArticleBiosensors2022

A Polypyrrole/Nanoclay Hybrid Film for Ultra-Sensitive Cardiac Troponin T Electrochemical Immunosensor.

Vicente P A Landim, Marcos V Foguel, Cecília M Prado, Maria P T Sotomayor, Iolanda C Vieira, Bárbara V M Silva, Rosa F Dutra

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The Alphabet of Nanostructured Polypyrrole.Materials (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Vicente P A LandimBiomedical Engineering Laboratory, Department of Biomedical Engineering, Federal University of Pernambuco, Av. Prof. Moraes Rego, 1235, Recife 50670-901, Brazil.
Marcos V FoguelBiomedical Engineering Laboratory, Department of Biomedical Engineering, Federal University of Pernambuco, Av. Prof. Moraes Rego, 1235, Recife 50670-901, Brazil.
Cecília M PradoBiomedical Engineering Laboratory, Department of Biomedical Engineering, Federal University of Pernambuco, Av. Prof. Moraes Rego, 1235, Recife 50670-901, Brazil.ORCID 0000-0002-0761-8247
Maria P T SotomayorInstitute of Chemistry, State University of São Paulo (UNESP), Araraquara 14801-970, Brazil.
Iolanda C VieiraLaboratory of Biosensors, Department of Chemistry, Federal University of Santa Catarina (UFSC), Florianopolis 88040-900, Brazil.
Bárbara V M SilvaBiomedical Engineering Laboratory, Department of Biomedical Engineering, Federal University of Pernambuco, Av. Prof. Moraes Rego, 1235, Recife 50670-901, Brazil.
Rosa F DutraBiomedical Engineering Laboratory, Department of Biomedical Engineering, Federal University of Pernambuco, Av. Prof. Moraes Rego, 1235, Recife 50670-901, Brazil.ORCID 0000-0001-8314-4218
Universidade Federal de Pernambuco · BRUniversidade de São Paulo · BRUniversidade Federal de Santa Catarina · BR

Funding

CAPES - BRazil 8888-01National Council for Scientific and Technological Development 44060520164
6 · The paper itself

Abstract

An electrochemical immunosensor based on a nanohybrid film of carboxylated polypyrrole and amine nanoclay was developed for label-free detection of the human cardiac troponin T (cTnT). The nanohybrid film was formed in situ on the surface of the glassy carbon electrode, followed by the covalent immobilization of anti-troponin T antibodies by glutaraldehyde. Morphological and chemical characterizations of the nanohybrid film were performed by scanning electron microscopy and Fourier-transform infrared spectroscopy. Under the optimized conditions, a calibration curve for cTnT in spiked serum was obtained by square wave voltammetry, and a low limit of detection and quantification was achieved (0.35 and 1.05 pg mL

Indexed as

Biosensing TechniquesPolymersElectrochemical TechniquesElectrodesHumansImmunoassayLimit of DetectionPyrrolesTroponin TPolymerspolypyrrolePyrrolesTroponin Tcardiac troponin Timmunosensornanoclaypolypyrrole

Identifiers

PMID35884348
PMCPMC9313248
OpenAlexW4286492417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.