Evidence map›Paper›PMID 35884301›Full record

ReviewBiosensors2022

Emerging Biosensors for Oral Cancer Detection and Diagnosis-A Review Unravelling Their Role in Past and Present Advancements in the Field of Early Diagnosis.

Vidhya Rekha Umapathy, Prabhu Manickam Natarajan, Bhuminathan Swamikannu, Johnson Moses, Sumathi Jones, Manoj Prathap Chandran, Madurai Kannan Anbumozhi

Abstract readReview
In one paragraph

Review in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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  7. Article
  8. Article
  9. Review
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  11. microRNA-based electrochemical biosensor for early detection of pulmonary arterial hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vidhya Rekha UmapathyDepartment of Public Health Dentistry, Sree Balaji Dental College and Hospital, Pallikaranai, Chennai 600 100, India.ORCID 0000-0002-8603-9373
Prabhu Manickam NatarajanDepartment of Periodontics, College of Dentistry, Ajman University, Ajman P.O. Box 346, United Arab Emirates.
Bhuminathan SwamikannuDepartment of Prosthodontics, Sree Balaji Dental College and Hospital, Pallikaranai, Chennai 600 100, India.
Johnson MosesDepartment of Anatomy, Sree Balaji Medical College and Hospital, Chromepet, Chennai 600 044, India.
Sumathi JonesDepartment of Pharmacology, Sree Balaji Dental College and Hospital, Pallikaranai, Chennai 600 100, India.ORCID 0000-0003-3192-6247
Manoj Prathap ChandranJunior Research Fellow, Sree Balaji Dental College and Hospital, Pallikaranai, Chennai 600 100, India.
Madurai Kannan AnbumozhiDepartment of Pathology, Sree Balaji Medical College and Hospital, Chromepet, Chennai 600 044, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral cancer is a serious concern to people all over the world because of its high mortality rate and metastatic spread to other areas of the body. Despite recent advancements in biomedical research, OC detection at an early stage remains a challenge and is complex and inaccurate with conventional diagnostics procedures. It is critical to study innovative approaches that can enable a faster, easier, non-invasive, and more precise diagnosis of OC in order to increase the survival rate of patients. In this paper, we conducted a review on how biosensors might be an excellent tool for detecting OC. This review covers the strategies that use different biosensors to target various types of biomarkers and focuses on biosensors that function at the molecular level viz. DNA biosensors, RNA biosensors, and protein biosensors. In addition, we reviewed non-invasive electrochemical methods, optical methods, and nano biosensors to analyze the OC biomarkers present in body fluids such as saliva and serum. As a result, this review sheds light on the development of ground-breaking biosensors for the early detection and diagnosis of OC.

Indexed as

Biosensing TechniquesMouth NeoplasmsBiomarkersEarly Detection of CancerElectrochemical TechniquesHumansBiomarkersbiomarkersbiosensorselectrochemical biosensornano biosensoroptical biosensororal cancersaliva

Identifiers

PMID35884301
PMCPMC9312890

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.