Evidence map›Paper›PMID 35884294›Full record

ArticleBiosensors2022

Machine Learning-Enabled Prediction of 3D-Printed Microneedle Features.

Misagh Rezapour Sarabi, M Munzer Alseed, Ahmet Agah Karagoz, Savas Tasoglu

Abstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Smart micro/nanoneedles for gene delivery.Iranian journal of basic medical sciences · 2026
    Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. AI-Based Metamaterial Design.ACS applied materials & interfaces · 2024
    Review
  15. Let's Print an Ecology in 3D (and 4D).Materials (Basel, Switzerland) · 2024
    Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Misagh Rezapour SarabiGraduate School of Sciences & Engineering, Koç University, Istanbul 34450, Turkey.ORCID 0000-0002-5295-5701
M Munzer AlseedBoğaziçi Institute of Biomedical Engineering, Boğaziçi University, Istanbul 34684, Turkey.
Ahmet Agah KaragozGraduate School of Sciences & Engineering, Koç University, Istanbul 34450, Turkey.
Savas TasogluGraduate School of Sciences & Engineering, Koç University, Istanbul 34450, Turkey.ORCID 0000-0003-4604-217X

Funding

Alexander von Humboldt Research Fellowship for Experienced ResearchersBilim Kahramanlari Dernegi The Young Scientist AwardMarie Skłodowska-Curie Individual Fellowship 101003361Outstanding Young Scientists Awards (GEBİP)Royal Academy Newton-Katip Çelebi Transforming Systems Through Partnership awardScience Academy's Young Scientist Awards Program (BAGEP)Tubitak 2232 International Fellowship for Outstanding Researchers Award 118C391
6 · The paper itself

Abstract

Microneedles (MNs) introduced a novel injection alternative to conventional needles, offering a decreased administration pain and phobia along with more efficient transdermal and intradermal drug delivery/sample collecting. 3D printing methods have emerged in the field of MNs for their time- and cost-efficient manufacturing. Tuning 3D printing parameters with artificial intelligence (AI), including machine learning (ML) and deep learning (DL), is an emerging multidisciplinary field for optimization of manufacturing biomedical devices. Herein, we presented an AI framework to assess and predict 3D-printed MN features. Biodegradable MNs were fabricated using fused deposition modeling (FDM) 3D printing technology followed by chemical etching to enhance their geometrical precision. DL was used for quality control and anomaly detection in the fabricated MNAs. Ten different MN designs and various etching exposure doses were used create a data library to train ML models for extraction of similarity metrics in order to predict new fabrication outcomes when the mentioned parameters were adjusted. The integration of AI-enabled prediction with 3D printed MNs will facilitate the development of new healthcare systems and advancement of MNs' biomedical applications.

Indexed as

Artificial IntelligenceNeedlesAdministration, CutaneousDrug Delivery SystemsMachine LearningPrinting, Three-Dimensional3D printingartificial intelligencedeep learningimage processingmachine learningmicroneedles

Identifiers

PMID35884294
PMCPMC9313436

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.