ArticleBiosensors2022
Multifrequency Investigation of Single- and Double-Stranded DNA with Scalable Metamaterial-Based THz Biosensors.
Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Review
- Design of a polarization-insensitive terahertz metamaterial biosensor for glioma tissue identification.Biomedical optics express · 2025Article
- Identifying phenotypes of colorectal malignant tumors using the quasi-bound state in the continuum of a terahertz metasurface biosensor.Biomedical optics express · 2025Article
- A Reflective Terahertz Point Source Meta-Sensor with Asymmetric Meta-Atoms for High-Sensitivity Bio-Sensing.Biosensors · 2024Article
- Exploring the Application of Terahertz Metamaterials Based on Metallic Strip Structures in Detection of Reverse Micelles.Biosensors · 2024Article
- High specificity THz metamaterial-based biosensor for label-free transcription factor detection in melanoma diagnostics.Scientific reports · 2023Article
- Numerical Investigation of GaN HEMT Terahertz Detection Model Considering Multiple Scattering Mechanisms.Nanomaterials (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Due to the occurrence of THz-excited vibrational modes in biomacromolecules, the THz frequency range has been identified as particularly suitable for developing and applying new bioanalytical methods. We present a scalable THz metamaterial-based biosensor being utilized for the multifrequency investigation of single- and double-stranded DNA (ssDNA and dsDNA) samples. It is demonstrated that the metamaterial resonance frequency shift by the DNA's presence depends on frequency. Our experiments with the scalable THz biosensors demonstrate a major change in the degree of the power function for dsDNA by 1.53 ± 0.06 and, in comparison, 0.34 ± 0.11 for ssDNA as a function of metamaterial resonance frequency. Thus, there is a significant advantage for dsDNA detection that can be used for increased sensitivity of biomolecular detection at higher frequencies. This work represents a first step for application-specific biosensors with potential advantages in sensitivity, specificity, and robustness.
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