ArticleBiosensors2022
Generalized Analytical Model for Enzymatic BioFET Transistors.
Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
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- Photoelectrochemical Enzyme Biosensor for Malate Using Quantum Dots on Indium Tin Oxide/Plastics as a Sensing Surface.Biosensors · 2023Article
- Article
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Authors and funding
4 authors.
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Abstract
Software tools that are able to simulate the functionality or interactions of an enzyme biosensor with Metal Oxide Semiconductor (MOS), or any Field Effect Transistor (FET) as transducer, represent a gap in the market. Bio-devices, or Enzyme-FET, cannot be simulated by Atlas or equivalent software. This paper resolves this issue for the enzymatic block coupled with FETs' role within biosensors. The first block has the concentration of biological analyte as the input signal and concentration of ions from the enzymatic reaction as the output signal. The modeling begins from the Michaelis-Menten formalism and analyzes the time dependence of the product concentrations that become the input signal for the next FET block. Comparisons within experimental data are provided. The analytical model proposed in this paper represents a general analytical tool in the design stage for enzymatic transistors used in clinical practices.
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