Evidence map›Paper›PMID 35884252›Full record

ArticleBiosensors2022

APTES-Modified Remote Self-Assembled DNA-Based Electrochemical Biosensor for Human Papillomavirus DNA Detection.

Yuxing Yang, Yang Qing, Xudong Hao, Chenxin Fang, Ping Ouyang, Haiyu Li, Zhencui Wang, Yazhen Liao, Haobin Fang, Jie Du

Abstract read
In one paragraph

Article in Biosensors, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Interactions of the DNA Nanostructure with Silane-Based Self-Assembled Monolayers.Langmuir : the ACS journal of surfaces and colloids · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuxing YangCollege of Materials Science and Engineering, Hainan University, Haikou 570228, China.
Yang QingCollege of Materials Science and Engineering, Hainan University, Haikou 570228, China.
Xudong HaoCollege of Materials Science and Engineering, Hainan University, Haikou 570228, China.
Chenxin FangCollege of Materials Science and Engineering, Hainan University, Haikou 570228, China.
Ping OuyangCollege of Materials Science and Engineering, Hainan University, Haikou 570228, China.
Haiyu LiCollege of Materials Science and Engineering, Hainan University, Haikou 570228, China.
Zhencui WangCollege of Materials Science and Engineering, Hainan University, Haikou 570228, China.
Yazhen LiaoCollege of Materials Science and Engineering, Hainan University, Haikou 570228, China.
Haobin FangCollege of Materials Science and Engineering, Hainan University, Haikou 570228, China.
Jie DuCollege of Materials Science and Engineering, Hainan University, Haikou 570228, China.ORCID 0000-0002-0529-5253

Funding

Graduate Students Innovation Research Project of Hainan Province Hys2020-35National Natural Science Foundation of China 21404028National Natural Science Foundation of China 21763009
6 · The paper itself

Abstract

High-risk human papillomavirus (HPV) infection is an important cause of cervical cancer formation; therefore, being able to detect high-risk HPV (e.g., HPV-16) is important for the early treatment and prevention of cervical cancer. In this study, a combination of a 3-aminopropyltriethoxysilane (APTES) modified gold electrode and a super sandwich structure was creatively developed, resulting in the development of a biosensor that is both sensitive and stable for the detection of HPV-16. The electrochemical biosensor possesses a lower detection limit compared with previous studies with an LOD of 5.475 × 10

Indexed as

Biosensing TechniquesMetal NanoparticlesPapillomavirus InfectionsUterine Cervical NeoplasmsDNAElectrochemical TechniquesElectrodesFemaleGoldHuman papillomavirus 16HumansLimit of DetectionPropylaminesSilanesamino-propyl-triethoxysilaneDNAGoldPropylaminesSilanes3-aminopropyltriethoxysilanecervical cancerelectrochemical detectionsuper sandwich structure

Identifiers

PMID35884252
PMCPMC9312881

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.