Evidence map›Paper›PMID 35884208›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Effectiveness of Intramammary Antibiotics, Internal Teat Sealants, or Both at Dry-Off in Dairy Cows: Clinical Mastitis and Culling Outcomes.

Sharif S Aly, Emmanuel Okello, Wagdy R ElAshmawy, Deniece R Williams, Randall J Anderson, Paul Rossitto, Karen Tonooka, Kathy Glenn, Betsy Karle, Terry W Lehenbauer

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Emerging of Uncommon Chronic Mastitis FromTransboundary and emerging diseases · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Sharif S AlyVeterinary Medicine Teaching and Research Center, School of Veterinary Medicine, University of California, Davis, Tulare, CA 93277, USA.ORCID 0000-0003-0330-5013
Emmanuel OkelloVeterinary Medicine Teaching and Research Center, School of Veterinary Medicine, University of California, Davis, Tulare, CA 93277, USA.ORCID 0000-0002-1746-8385
Wagdy R ElAshmawyVeterinary Medicine Teaching and Research Center, School of Veterinary Medicine, University of California, Davis, Tulare, CA 93277, USA.ORCID 0000-0001-6466-1455
Deniece R WilliamsVeterinary Medicine Teaching and Research Center, School of Veterinary Medicine, University of California, Davis, Tulare, CA 93277, USA.ORCID 0000-0002-7534-732X
Randall J AndersonCalifornia Department of Food and Agriculture, Animal Health Branch, Sacramento, CA 95814, USA.
Paul RossittoVeterinary Medicine Teaching and Research Center, School of Veterinary Medicine, University of California, Davis, Tulare, CA 93277, USA.
Karen TonookaVeterinary Medicine Teaching and Research Center, School of Veterinary Medicine, University of California, Davis, Tulare, CA 93277, USA.
Kathy GlennVeterinary Medicine Teaching and Research Center, School of Veterinary Medicine, University of California, Davis, Tulare, CA 93277, USA.
Betsy KarleCooperative Extension, Division of Agriculture and Natural Resources, University of California, Orland, CA 95963, USA.
Terry W LehenbauerVeterinary Medicine Teaching and Research Center, School of Veterinary Medicine, University of California, Davis, Tulare, CA 93277, USA.
University of California, Davis · USCairo University · EGCalifornia Department of Food and Agriculture · USUniversity of California Division of Agriculture and Natural Resources · US

Funding

University of California System UC ANR Grant No. 3765; PI Sharif Aly
6 · The paper itself

Abstract

Intramammary antibiotic (AB) and internal teat sealants (TS) infusion at dry-off have been used to prevent intramammary infections (IMI) in dairy cows during the dry period and reduce the risk of mastitis during the dry period and subsequent lactation. A randomized clinal trial was completed on eight California dairy herds to estimate the effects of different dry cow therapies (AB, TS, AB + TS or None) on clinical mastitis and culling. A total of 1273 cows were randomized to one of the four treatment groups over summer and winter seasons. For each enrolled cow, microbiological testing was done on quarter milk samples collected from the first detection of clinical mastitis within the first 150 days in milk (DIM) in the subsequent lactation. Statistical analysis was done using generalized linear mixed models. There were no significant differences in the odds of clinical mastitis or culling between cows treated with AB, TS, or AB + TS compared to the controls. Dry cow therapy with AB and/or TS had no statistically significant effect on clinical mastitis and cow culling during the first 150 DIM.

Indexed as

California mastitis testcullingdry cow therapymastitissubclinical mastitisteat end scoreudder hygiene

Identifiers

PMID35884208
PMCPMC9311672
OpenAlexW4285734045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.