Evidence map›Paper›PMID 35884156›Full record

ArticleAntibiotics (Basel, Switzerland)2022

Antibacterial Activity against Clinical Isolates and In Vivo Efficacy of Coralmycins.

Ha-Young Choi, Bo-Min Kim, Young-Rok Kim, Taehui Yang, Sunjoo Ahn, Dongeun Yong, Jin-Hwan Kwak, Won-Gon Kim

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Ha-Young ChoiInfectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Yusong, Daejeon 34141, Korea.
Bo-Min KimInfectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Yusong, Daejeon 34141, Korea.
Young-Rok KimSchool of Life Science, Handong Global University, Pohang 37554, Korea.
Taehui YangInfectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Yusong, Daejeon 34141, Korea.ORCID 0000-0002-7374-3281
Sunjoo AhnBio and Drug Discovery Division, Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yusong, Daejeon 34114, Korea.
Dongeun YongDepartment of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID 0000-0002-1225-8477
Jin-Hwan KwakSchool of Life Science, Handong Global University, Pohang 37554, Korea.ORCID 0000-0003-3613-5380
Won-Gon KimInfectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Yusong, Daejeon 34141, Korea.
Korea Research Institute of Bioscience and Biotechnology · KRHandong Global University · KRKorea Research Institute of Chemical Technology · KRYonsei University · KR

Funding

Korea Health Industry Development Institute HI17C1807Korea Research Institute of Bioscience and Technology KGM2112234National Research Foundation of Korea NRF-2021R1I1A2048905
6 · The paper itself

Abstract

Coralmycins, such as coralmycin A and DH-coralmycin A, have novel molecular skeletons and have been reported to exhibit potent antibacterial activity against standard Gram-positive bacterial strains. Here, the in vitro antibacterial activity against an extensive clinical isolate collection, time-kill kinetics, pharmacokinetics (PK), and in vivo efficacy of coralmycins were studied. Coralmycin A showed potent antibacterial activity with an MIC

Indexed as

antibacterialcoralmycinsin vivo efficacymultidrug-resistant Gram-positive bacteriapharmacokinetics

Identifiers

PMID35884156
PMCPMC9311539
OpenAlexW4283834278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.