Evidence map›Paper›PMID 35884109›Full record

ReviewAntibiotics (Basel, Switzerland)2022

Synergistic Role of Plant Extracts and Essential Oils against Multidrug Resistance and Gram-Negative Bacterial Strains Producing Extended-Spectrum β-Lactamases.

Manzar Alam, Nilofer Bano, Taufeeq Ahmad, Amit Baran Sharangi, Tarun Kumar Upadhyay, Yasser Alraey, Nadiyah M Alabdallah, Mohd Ahmar Rauf, Mohd Saeed

Open access · goldAbstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 52 citations in OpenAlex.

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  15. Effect of DifferentMolecules (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 3 countries.

Manzar AlamDepartment of Biosciences, Integral University, Lucknow 226026, India.
Nilofer BanoDepartment of Bioengineering, Integral University, Lucknow 226026, India.
Taufeeq AhmadFaculty of Biosciences, Shri Ramswaroop Memorial University, Lucknow 225003, India.
Amit Baran SharangiDepartment of Plantation Spices Medicinal and Aromatic Crops, Bidhan Chandra Krishi Viswavidyalaya, Mohanpur 741252, India.ORCID 0000-0001-6630-5999
Tarun Kumar UpadhyayDepartment of Biotechnology, Parul Institute of Applied Sciences and Centre of Research for Development, Parul University, Vadodara 391760, India.ORCID 0000-0002-2551-9779
Yasser AlraeyDepartment of Clinical Laboratory Sciences, Central Research Laboratory, College of Applied Medical Sciences, King Khalid University, Abha 62559, Saudi Arabia.ORCID 0000-0002-5809-7525
Nadiyah M AlabdallahDepartment of Biology, College of Science, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.
Mohd Ahmar RaufDepartment of Pharmaceutical Sciences, Wayne State University, Detroit, MI 48201, USA.ORCID 0000-0001-5639-2208
Mohd SaeedDepartment of Biology, College of Sciences, University of Hail, Hail 4464, Saudi Arabia.ORCID 0000-0003-3443-386X
Integral University · INBidhan Chandra Krishi Viswavidyalaya · INImam Abdulrahman Bin Faisal University · SAKing Khalid University · SAParul University · INShri Ramswaroop Memorial University · INUniversity of Ha'il · SAWayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants, being the significant and natural source of medication for humankind against several ailments with characteristic substances hidden on them, have been recognized for many centuries. Accessibility of various methodologies for the revelation of therapeutically characteristic items has opened new avenues to redefine plants as the best reservoirs of new structural types. The role of plant metabolites to hinder the development and movement of pathogenic microbes is cherished. Production of extended-spectrum β-lactamases is an amazing tolerance mechanism that hinders the antibacterial treatment of infections caused by Gram-negative bacteria and is a serious problem for the current antimicrobial compounds. The exploration of the invention from sources of plant metabolites gives sustenance against the concern of the development of resistant pathogens. Essential oils are volatile, natural, complex compounds described by a solid odor and are framed by aromatic plants as secondary metabolites. The bioactive properties of essential oils are commonly controlled by the characteristic compounds present in them. They have been commonly utilized for bactericidal, virucidal, fungicidal, antiparasitic, insecticidal, medicinal, and antioxidant applications. Alkaloids are plant secondary metabolites that have appeared to have strong pharmacological properties. The impact of alkaloids from

Indexed as

antimicrobial resistanceantioxidantextended-spectrum β-lactamasespathogenic microbesplant extract and essential oilsynergistic effect

Identifiers

PMID35884109
PMCPMC9312036
OpenAlexW4283586904

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.