Evidence map›Paper›PMID 35884073›Full record

ArticleChildren (Basel, Switzerland)2022

Survey on Untethering of the Spinal Cord and Urological Manifestations among Spina Bifida Patients in Malaysia.

Singh Nisheljeet, Abu Bakar Azizi, Kamalanathan Palaniandy, Dharmendra Ganesan, Teng Aik Ong, Azmi Alias, Ramalinggam Rajamanickam, Wahib M Atroosh, Siti Waheeda Mohd-Zin, Andrea Lee-Shamsuddin and 3 more

Open access · goldAbstract read
In one paragraph

Article in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Singh NisheljeetInvertebrate & Vertebrate Neurobiology Lab, Department of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia.
Abu Bakar AziziDepartment of Surgery, University Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.
Kamalanathan PalaniandyDepartment of Surgery, University Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.
Dharmendra GanesanDepartment of Surgery, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia.
Teng Aik OngDepartment of Surgery, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia.
Azmi AliasDepartment of Neurosurgery, Tunku Abdul Rahman Neuroscience Institute (IKTAR), Hospital Kuala Lumpur, Kuala Lumpur 50586, Malaysia.
Ramalinggam RajamanickamFaculty of Law, Universiti Kebangsaan Malaysia, Kuala Lumpur 43600, Malaysia.
Wahib M AtrooshDepartment of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia.ORCID 0000-0003-3809-3460
Siti Waheeda Mohd-ZinInvertebrate & Vertebrate Neurobiology Lab, Department of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia.
Andrea Lee-ShamsuddinInvertebrate & Vertebrate Neurobiology Lab, Department of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia.
Singh NivrenjeetInvertebrate & Vertebrate Neurobiology Lab, Department of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia.
Warren LoDepartment of Urology, Kuala Lumpur Hospital, Jalan Pahang, Kuala Lumpur 50586, Malaysia.
Noraishah Mydin Abdul-AzizInvertebrate & Vertebrate Neurobiology Lab, Department of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia.ORCID 0000-0002-2447-3211
University of Malaya · MYHospital Kuala Lumpur · MYUniversity Kebangsaan Malaysia Medical Centre · MYNational University of Malaysia · MY

Funding

Fundamental Research Grant Scheme FRGS/1/2019/SKK06/UKM/02/06Fundamental Research Grant Scheme FRGS/1/2019/SKK08/UM/02/17 (FP090-2019A)
6 · The paper itself

Abstract

The incidence and severity of urinary tract infections (UTIs) due to spina bifida is poorly understood in Malaysia. Tethering of the spinal cord is a pathological fixation of the cord in the vertebral column that can result in neurogenic bladder dysfunction and other neurological problems. It occurs in patients with spina bifida, and the authors of this study sought to investigate the impact of untethering on the urological manifestations of children with a tethered cord, thereby consolidating a previously known understanding that untethering improves bladder and bowel function. Demographic and clinical data were collected via an online questionnaire and convenient sampling techniques were used. A total of 49 individuals affected by spina bifida participated in this study. UTIs were reported based on patients' observation of cloudy and smelly urine (67%) as well as urine validation (60%). UTI is defined as the combination of symptoms and factoring in urine culture results that eventually affects the UTI diagnosis in spina bifida individuals irrespective of CISC status. Furthermore, 18% of the respondents reported being prescribed antibiotics even though they had no history of UTI. Therefore, indiscriminate prescription of antibiotics by healthcare workers further compounds the severity of future UTIs. Employing CISC (73%) including stringent usage of sterile catheters (71%) did not prevent patients from getting UTI. Overall, 33% of our respondents reported manageable control of UTI (0-35 years of age). All individuals below the age of 5 (100%,

Indexed as

antibiotic stewardshipspina bifidaurinary tract infectionurological management

Identifiers

PMID35884073
PMCPMC9324435
OpenAlexW4286499329

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.