Evidence map›Paper›PMID 35884034›Full record

ReviewChildren (Basel, Switzerland)2022

AGREEing on Clinical Practice Guidelines for Autism Spectrum Disorders in Children: A Systematic Review and Quality Assessment.

Yasser S Amer, Shuliweeh Alenezi, Fahad A Bashiri, Amel Hussain Alawami, Ayman Shawqi Alhazmi, Somayyah A Aladamawi, Faisal Alnemary, Yasser Alqahtani, Maysaa W Buraik, Saleh S AlSuwailem and 4 more

Abstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Gross Motor Development in Children With Autism: Longitudinal Trajectories From the Growing Up in New Zealand Study.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yasser S AmerPediatrics Department, King Khalid University Hospital, King Saud University Medical City, Riyadh 11451, Saudi Arabia.ORCID 0000-0003-4097-2317
Shuliweeh AleneziDepartment of Psychiatry, College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-7049-0960
Fahad A BashiriPediatric Neurology Division, Pediatrics Department, College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia.ORCID 0000-0003-1436-6727
Amel Hussain AlawamiJohns Hopkins Aramco Healthcare, Dhahran 34465, Saudi Arabia.
Ayman Shawqi AlhazmiDevelopmental Pediatric Department, Children's Hospital, King Saud Medical City, Ministry of Health, Riyadh 12746, Saudi Arabia.
Somayyah A AladamawiKing Abdullah bin Abdulaziz University Hospital, Riyadh 11564, Saudi Arabia.
Faisal AlnemaryAutism Center of Excellence, Riyadh 11564, Saudi Arabia.
Yasser AlqahtaniKing Fahad Armed Forces Hospital, Jeddah 23311, Saudi Arabia.
Maysaa W BuraikJohns Hopkins Aramco Healthcare, Dhahran 34465, Saudi Arabia.
Saleh S AlSuwailemAutism Center of Excellence, Riyadh 11564, Saudi Arabia.
Shahad M AkhalifahAutism Center of Excellence, Riyadh 11564, Saudi Arabia.
Marcela Augusta de Souza PinhelDepartment of Health Science, Ribeirao Preto Medical School, University of São Paulo, Ribeirao Preto 14049-900, Brazil.
Melanie PennerHolland Bloorview Kids Rehabilitation Hospital, Toronto, ON M4G 1R8, Canada.
Ahmed M ElmalkyMorbidity and Mortality Unit, King Saud University Medical City, King Saud University, Riyadh 11451, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAutism spectrum disorder (ASD) is a multifaceted neurodevelopmental disorder requiring multimodal intervention and an army of multidisciplinary teams for a proper rehabilitation plan. Accordingly, multiple practice guidelines have been published for different disciplines. However, systematic evidence to detect and intervene must be updated regularly. Our main objective is to compare and summarize the recommendations made in the clinical practice guidelines (CPGs) for ASD in children released from November 2015 to March 2022.

methodsCPGs were subjected to a systematic review. We developed the inclusion and exclusion criteria and health-related questions, then searched and screened for CPGs utilizing bibliographic and CPG databases. Each of the CPGs used in the study were critically evaluated using the Appraisal of Guidelines for REsearch and Evaluation II (AGREE II) instrument. In a realistic comparison table, we summarized the recommendations.

resultsFour eligible CPGs were appraised: Australian Autism CRC (ACRC); Ministry of Health New Zealand (NZ); National Institute for Health and Care Excellence (NICE); and Scottish Intercollegiate Guidelines Network, Healthcare Improvement Scotland (SIGN-HIS). The overall assessments of all four CPGs scored greater than 80%; these findings were consistent with the high scores in the six domains of AGREE II, including: (1) scope and purpose, (2) stakeholder involvement, (3) rigor of development, (4) clarity of presentation, (5) applicability, and (6) editorial independence domains. Domain (3) scored 84%, 93%, 86%, and 85%; domain (5) 92%, 89%, 54%, and 85%; and domain (6) 92%, 96%, 88%, and 92% for ACRC, NICE, NZ, and SIGN-HIS, respectively. Overall, there were no serious conflicts between the clinical recommendations of the four CPGs, but some were more comprehensive and elaborative than others.

conclusionsAll four assessed evidence-based CPGs demonstrated high methodological quality and relevance for use in practice.

Indexed as

AGREE II instrumentautism spectrum disorderclinical practice guidelinespediatricspsychiatryquality assessmentsystematic review

Identifiers

PMID35884034
PMCPMC9323940

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.