ArticleAntioxidants (Basel, Switzerland)2022
Changes in Biomarkers of Redox Status in Saliva of Pigs after an Experimental Sepsis Induction.
Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- The Salivary Microbiota-Host Nexus: Unraveling Opportunities for Non-Invasive Monitoring of Health and Productivity in Farm Animals.Animals : an open access journal from MDPI · 2026Review
- Sodium thiosulfate attenuates liver injury in a rat model of sepsis by modulating ferroptosis and oxidative stress.Scientific reports · 2025Article
- Changes in saliva and serum analytes in domestic pigs and wild boar experimentally infected with African swine fever virus.Veterinary research · 2025Article
- Article
- Use of Saliva Analytes as a Predictive Model to Detect Diseases in the Pig: A Pilot Study.Metabolites · 2025Article
- Stress Biomarkers in Pigs: Current Insights and Clinical Application.Veterinary sciences · 2024Review
- Evaluation of Glutathione (GSH) System in Porcine Saliva: Validation and Application of Colorimetric Method.Antioxidants (Basel, Switzerland) · 2024Article
- Non-invasive methods for analysing pig welfare biomarkers.Veterinarni medicina · 2024Review
- Performance and overview of clinically relevant areas of application of saliva testing in the cat.Frontiers in veterinary science · 2024Review
- Changes in S100A8/A9 and S100A12 and Their Comparison with Other Analytes in the Saliva of Pigs with Diarrhea Due toAnimals : an open access journal from MDPI · 2023Article
- Changes in salivary biomarkers of stress, inflammation, redox status, and muscle damage due to Streptococcus suis infection in pigs.BMC veterinary research · 2023Article
- Measurement of Calprotectin (S100A8/A9) in the Saliva of Pigs: Validation Data of A Commercially Available Automated Assay and Changes in Sepsis, Inflammation, and Stress.Animals : an open access journal from MDPI · 2023Article
- Evaluation of the Effect of Sampling Time on Biomarkers of Stress, Immune System, Redox Status and Other Biochemistry Analytes in Saliva of Finishing Pigs.Animals : an open access journal from MDPI · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Saliva from pigs is gaining attention as an easy sample to obtain, being a source of biomarkers that can provide information on animal health and welfare. This study aimed to evaluate the changes that can occur in salivary biomarkers of the redox status of pigs with an experimentally induced sepsis. For that, the cupric reducing antioxidant capacity (CUPRAC), ferric reducing ability of saliva (FRAS), Trolox equivalent antioxidant capacity (TEAC), advanced oxidation protein products (AOPP), ferrous oxidation-xylenol orange (FOX), peroxide activity (POX-Act), and reactive oxygen-derived compounds (d-ROMs) were measured in the saliva of pigs with experimentally induced sepsis by endotoxin lipopolysaccharide (LPS), non-septic inflammation induced by turpentine, and in healthy individuals before and after 3 h, 6 h, 24 h, and 48 h. AOPP, POX-Act, and d-ROMs in the sepsis group were higher than in the control from 3 h to 24 h after the inoculation. CUPRAC, FRAS, and TEAC were higher in sepsis than the control group at 24 h. These changes were of higher magnitude than those that occurred in the turpentine group. In conclusion, our findings reveal that sepsis produces changes in salivary biomarkers of redox status, which opens the possibility of using them as potential biomarkers in this species.
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