ArticleAntioxidants (Basel, Switzerland)2022
Dim Blue Light at Night Induces Spatial Memory Impairment in Mice by Hippocampal Neuroinflammation and Oxidative Stress.
Article in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 47 citations in OpenAlex.
- Nocturnal Dim Blue Light Is Associated with Splenic Immune Dysregulation and Altered CORT-GR Signalling in High-Fat-Diet-Fed Mice.Antioxidants (Basel, Switzerland) · 2026Article
- Chronic exposure to LED lighting impairs prefrontal cortex-dependent cognitive functions in adolescent rats.Scientific reports · 2026Article
- Article
- Effects of Exposure to Extreme Artificial Light at Night on Liver Oxidative Damage and Gut Microbiota During Pregnancy and Lactation in Mice.Animals : an open access journal from MDPI · 2026Article
- Mitigating Blue-Light Risk in Display-Based Digital Therapeutics: A Practical Framework to Support Clinical Efficacy.Journal of clinical medicine · 2026Review
- Neural mechanisms of the V2M-PrL pathway mediate blue light-induced spatial memory impairment.Communications biology · 2025Article
- Low-Intensity Constant Light During Early Postnatal Development Induces Sex-Specific Anxiety-Like Behaviour and Region- and Sex-Specific Changes in Circadian Gene Expression and RNA Editing.Cellular and molecular neurobiology · 2025Article
- Midnight darkness and evening melatonin pre-treatment reverse night-light-induced neurobehavioural disruptions in a diurnal corvid.Scientific reports · 2025Article
- Blue light treatment of psychiatric disorders: relationships with systemic inflammation, lipid metabolism, and clinical symptoms.BMC psychiatry · 2025Article
- Physiological Responses Vary with Molecular Damage Outcomes after Recovery from Constant Light.Integrative and comparative biology · 2025Article
- Dim light at night impacts circadian rhythms and Alzheimer's disease-like neuroinflammation and neuropathology in humanized APP SAA knock-in mice.bioRxiv : the preprint server for biology · 2025Article
- Effects of air and light pollution on brain and behavioral function: Potential synergy.Neuroscience and biobehavioral reviews · 2025Review
- Hypothalamic Orexin Projections to the Hippocampal CA1 Region Alleviate Cognitive and Synaptic Plasticity Impairments Induced by Blue Light Exposure.CNS neuroscience & therapeutics · 2025Article
- Circadian clock and its effect on aging and lifespan.Biogerontology · 2025Review
- Article
- Light at night exposure and risk of dementia conversion from mild cognitive impairment in a Northern Italy population.International journal of health geographics · 2024Article
- Repeated intrathecal injections of peripheral nerve-derived stem cell spheroids improve outcomes in a rat model of traumatic brain injury.Stem cell research & therapy · 2024Article
- The effects of artificial light at night on spider brains.Biology letters · 2024Article
- Light Pollution and Oxidative Stress: Effects on Retina and Human Health.Antioxidants (Basel, Switzerland) · 2024Review
- Artificial light at night suppresses the day-night cardiovascular variability: evidence from humans and rats.Pflugers Archiv : European journal of physiology · 2024Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Light pollution is one of the most serious public problems, especially the night light. However, the effect of dim blue light at night (dLAN-BL) on cognitive function is unclear. In this study, we evaluated the effects of exposure to dLAN-BL in C57BL/6J mice for 4 consecutive weeks. Our results showed dLAN-BL significantly impaired spatial learning and memory and increased plasma corticosterone level in mice. Consistent with these changes, we observed dLAN-BL significantly increased the numbers and activation of microglia and the levels of oxidative stress product MDA in the hippocampus, decreased the levels of antioxidant enzymes Glutathione peroxidase (GSH-Px), Superoxide dismutase (SOD), Gluathione reductase (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.