Evidence map›Paper›PMID 35883708›Full record

ReviewAntioxidants (Basel, Switzerland)2022

Protective Effects of Diets Rich in Polyphenols in Cigarette Smoke (CS)-Induced Oxidative Damages and Associated Health Implications.

Mithun Rudrapal, Siddhartha Maji, Shiv Kumar Prajapati, Payal Kesharwani, Prashanta Kumar Deb, Johra Khan, Randa Mohamed Ismail, Rani S Kankate, Ranjan Kumar Sahoo, Shubham J Khairnar and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
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  4. Review
  5. Role of Fruit-Derived Antioxidants in Fighting Cancer: A Narrative Review.Indian journal of clinical biochemistry : IJCB · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Mithun RudrapalDepartment of Pharmaceutical Chemistry, Rasiklal M. Dhariwal Institute of Pharmaceutical Education and Research, Pune 411019, Maharashtra, India.ORCID 0000-0002-8172-6633
Siddhartha MajiRamEesh Institute of Vocational and Technical Education, Greater Noida 201310, Uttar Pradesh, India.ORCID 0000-0001-7132-9573
Shiv Kumar PrajapatiRamEesh Institute of Vocational and Technical Education, Greater Noida 201310, Uttar Pradesh, India.
Payal KesharwaniRamEesh Institute of Vocational and Technical Education, Greater Noida 201310, Uttar Pradesh, India.
Prashanta Kumar DebDepartment of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan 173229, Himachal Pradesh, India.
Johra KhanDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences (CAMS), Majmaah University, Al Majmaah 11952, Saudi Arabia.ORCID 0000-0002-0044-4758
Randa Mohamed IsmailDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences (CAMS), Majmaah University, Al Majmaah 11952, Saudi Arabia.
Rani S KankateDepartment of Pharmaceutical Chemistry, MET's Institute of Pharmacy, Bhujbal Knowledge City, Nashik 422003, Maharashtra, India.ORCID 0000-0002-7569-0777
Ranjan Kumar SahooSchool of Pharmacy and Life Sciences, Centurion University of Technology and Management, Bhubaneswar 752050, Odisha, India.ORCID 0000-0002-9511-8188
Shubham J KhairnarDepartment of Pharmacology, MET's Institute of Pharmacy, Bhujbal Knowledge City, Nashik 422003, Maharashtra, India.
Atul R BendaleSandip Institute of Pharmaceutical Sciences, Nashik 422213, Maharashtra, India.ORCID 0000-0002-3219-0377
Majmaah University · SACenturion University of Technology and Management · INInstitute of Engineering · NPSandip Foundation · INShoolini University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cigarette smoking has been responsible for causing many life-threatening diseases such as pulmonary and cardiovascular diseases as well as lung cancer. One of the prominent health implications of cigarette smoking is the oxidative damage of cellular constituents, including proteins, lipids, and DNA. The oxidative damage is caused by reactive oxygen species (ROS, oxidants) present in the aqueous extract of cigarette smoke (CS). In recent years, there has been considerable interest in the potential health benefits of dietary polyphenols as natural antioxidant molecules. Epidemiological studies strongly suggest that long-term consumption of diets (fruits, vegetables, tea, and coffee) rich in polyphenols offer protective effects against the development of cancer, cardiovascular diseases, diabetes, osteoporosis, and neurodegenerative diseases. For instance, green tea has chemopreventive effects against CI-induced lung cancer. Tea might prevent CS-induced oxidative damages in diseases because tea polyphenols, such as catechin, EGCG, etc., have strong antioxidant properties. Moreover, apple polyphenols, including catechin and quercetin, provide protection against CS-induced acute lung injury such as chronic obstructive pulmonary disease (COPD). In CS-induced health problems, the antioxidant action is often accompanied by the anti-inflammatory effect of polyphenols. In this narrative review, the CS-induced oxidative damages and the associated health implications/pathological conditions (or diseases) and the role of diets rich in polyphenols and/or dietary polyphenolic compounds against various serious/chronic conditions of human health have been delineated.

Indexed as

bioavailabilitycardioprotectivecigarette smokeCOPDdietary polyphenolsoxidative damage

Identifiers

PMID35883708
PMCPMC9311530
OpenAlexW4283272052

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.