Evidence map›Paper›PMID 35883691›Full record

ArticleCells2022

Indirect Negative Effect of Mutant Ataxin-1 on Short- and Long-Term Synaptic Plasticity in Mouse Models of Spinocerebellar Ataxia Type 1.

Anton N Shuvaev, Olga S Belozor, Oleg I Mozhei, Andrey N Shuvaev, Yana V Fritsler, Elena D Khilazheva, Angelina I Mosyagina, Hirokazu Hirai, Anja G Teschemacher, Sergey Kasparov

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Anton N ShuvaevResearch Institute of Molecular Medicine and Pathobiochemistry, Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia.
Olga S BelozorResearch Institute of Molecular Medicine and Pathobiochemistry, Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia.
Oleg I MozheiInstitute of Living Systems, Immanuel Kant Baltic Federal University, 236041 Kaliningrad, Russia.ORCID 0000-0002-5427-1688
Andrey N ShuvaevInstitute of Fundamental Biology and Biotechnology, Siberian Federal University, 660041 Krasnoyarsk, Russia.
Yana V FritslerInstitute of Fundamental Biology and Biotechnology, Siberian Federal University, 660041 Krasnoyarsk, Russia.
Elena D KhilazhevaResearch Institute of Molecular Medicine and Pathobiochemistry, Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia.
Angelina I MosyaginaResearch Institute of Molecular Medicine and Pathobiochemistry, Krasnoyarsk State Medical University, 660022 Krasnoyarsk, Russia.ORCID 0000-0002-7344-7925
Hirokazu HiraiDepartment of Neurophysiology and Neural Repair, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.
Anja G TeschemacherDepartment of Physiology, Pharmacology, and Neuroscience, University of Bristol, Bristol BS8 1TH, UK.
Sergey KasparovInstitute of Living Systems, Immanuel Kant Baltic Federal University, 236041 Kaliningrad, Russia.
Krasnoyarsk State Medical University · RUImmanuel Kant Baltic Federal University · RUUniversity of Bristol · GBGunma University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spinocerebellar ataxia type 1 (SCA1) is an intractable progressive neurodegenerative disease that leads to a range of movement and motor defects and is eventually lethal. Purkinje cells (PC) are typically the first to show signs of degeneration. SCA1 is caused by an expansion of the polyglutamine tract in the

Indexed as

Spinocerebellar AtaxiasAnimalsAtaxin-1Disease Models, AnimalMiceMice, TransgenicNeuronal PlasticityPurkinje CellsAtaxin-1Atxn1 protein, mouseBergmann gliaDSELTDPPDPPFPurkinje cellsspinocerebellar ataxia type 1synaptic plasticity

Identifiers

PMID35883691
PMCPMC9317252
OpenAlexW4286209304

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.