Evidence map›Paper›PMID 35883677›Full record

ReviewCells2022

MicroRNAs and Long Non-Coding RNAs in Adrenocortical Carcinoma.

Mario Detomas, Claudia Pivonello, Bianca Pellegrini, Laura-Sophie Landwehr, Silviu Sbiera, Rosario Pivonello, Cristina L Ronchi, Annamaria Colao, Barbara Altieri, Maria Cristina De Martino

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Mario DetomasDepartment of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital Würzburg, University of Würzburg, 97080 Würzburg, Germany.ORCID 0000-0001-7864-6125
Claudia PivonelloDipartimento di Medicina Clinica e Chirurgia, Università "Federico II" di Napoli, 80131 Naples, Italy.ORCID 0000-0003-4276-8600
Bianca PellegriniDipartimento di Medicina Clinica e Chirurgia, Università "Federico II" di Napoli, 80131 Naples, Italy.ORCID 0000-0002-0496-8997
Laura-Sophie LandwehrDepartment of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital Würzburg, University of Würzburg, 97080 Würzburg, Germany.ORCID 0000-0002-6315-4176
Silviu SbieraDepartment of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital Würzburg, University of Würzburg, 97080 Würzburg, Germany.ORCID 0000-0002-6271-5533
Rosario PivonelloDipartimento di Medicina Clinica e Chirurgia, Università "Federico II" di Napoli, 80131 Naples, Italy.ORCID 0000-0002-9632-1348
Cristina L RonchiDepartment of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital Würzburg, University of Würzburg, 97080 Würzburg, Germany.ORCID 0000-0001-5020-2071
Annamaria ColaoDipartimento di Medicina Clinica e Chirurgia, Università "Federico II" di Napoli, 80131 Naples, Italy.
Barbara AltieriDepartment of Internal Medicine I, Division of Endocrinology and Diabetes, University Hospital Würzburg, University of Würzburg, 97080 Würzburg, Germany.ORCID 0000-0003-2616-3249
Maria Cristina De MartinoDipartimento di Medicina Clinica e Chirurgia, Università "Federico II" di Napoli, 80131 Naples, Italy.ORCID 0000-0003-3354-009X
University of Würzburg · DEUniversity of Naples Federico II · ITFederico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-coding RNAs (ncRNAs) are a type of genetic material that do not encode proteins but regulate the gene expression at an epigenetic level, such as microRNAs (miRNAs) and long non-coding RNAs (lncRNAs). The role played by ncRNAs in many physiological and pathological processes has gained attention during the last few decades, as they might be useful in the diagnosis, treatment and management of several human disorders, including endocrine and oncological diseases. Adrenocortical carcinoma (ACC) is a rare and aggressive endocrine cancer, still characterized by high mortality and morbidity due to both endocrine and oncological complications. Despite the rarity of this disease, recently, the role of ncRNA has been quite extensively evaluated in ACC. In order to better explore the role of the ncRNA in human ACC, this review summarizes the current knowledge on ncRNA dysregulation in ACC and its potential role in the diagnosis, treatment, and management of this tumor.

Indexed as

Adrenal Cortex NeoplasmsAdrenocortical CarcinomaMicroRNAsRNA, Long NoncodingHumansRNA, UntranslatedMicroRNAsRNA, Long NoncodingRNA, UntranslatedACCadrenocortical adenomaadrenocortical tumorlncRNAmiRNAprognostic markers

Identifiers

PMID35883677
PMCPMC9324008
OpenAlexW4285801025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.