Evidence map›Paper›PMID 35883643›Full record

ArticleCells2022

Endothelial Barrier Disruption by Lipid Emulsions Containing a High Amount of N3 Fatty Acids (Omegaven) but Not N6 Fatty Acids (Intralipid).

Emilie Gueguen, Yasser Morsy, Michael Scharl, Stefanie D Krämer, Michael Zaugg, Martin Hersberger, Gerhard Rogler, Marcin Wawrzyniak

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Emilie GueguenFaculty of Fundamental and Applied Sciences, University of Poitiers, 86000 Poitiers, France.ORCID 0000-0002-8187-8792
Yasser MorsyDepartment of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.ORCID 0000-0001-8234-1877
Michael ScharlDepartment of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.
Stefanie D KrämerInstitute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, 8039 Zurich, Switzerland.ORCID 0000-0002-0426-4340
Michael ZauggDepartment of Anesthesiology and Pain Medicine and Cardiovascular Research Centre, University of Alberta, Edmonton, AB T6G 2R3, Canada.
Martin HersbergerDivision of Clinical Chemistry and Biochemistry, University Children's Hospital Zurich, 8032 Zurich, Switzerland.
Gerhard RoglerDepartment of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.ORCID 0000-0002-1733-9188
Marcin WawrzyniakDepartment of Gastroenterology and Hepatology, University Hospital Zurich, University of Zurich, 8091 Zurich, Switzerland.ORCID 0000-0002-6911-8010
University of Zurich · CHETH Zurich · CHUniversity Children's Hospital Zurich · CHUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipid emulsions are crucial for life-saving total parenteral nutrition (TPN). Their composition provides a high amount of essential fatty acids and calories for millions of patients with serious diseases. Nevertheless, several TPN-mediated side-effects have been reported in over 90% of patients. This project aimed to investigate the effect of a high amount of ω3 fatty acids (Omegaven

Indexed as

Fatty AcidsFatty Acids, Omega-3EmulsionsEndothelial CellsEndotheliumFish OilsHumansTriglyceridesEmulsionsFatty AcidsFatty Acids, Omega-3Fish Oilsfish oil triglyceridesTriglyceridesendothelial barrierendothelial cellslipid emulsionsparenteral nutrition

Identifiers

PMID35883643
PMCPMC9320111
OpenAlexW4285596717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.