Evidence map›Paper›PMID 35883626›Full record

ReviewCells2022

Crucial Role of Oncogenic

Anabela Ferreira, Flávia Pereira, Celso Reis, Maria José Oliveira, Maria João Sousa, Ana Preto

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 85 citations in OpenAlex.

  1. Article
  2. Article
  3. Canon enables causal inference of downstream genes in single-cell CRISPR studies via instrumental variable analysis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Autophagy in Ovarian Cancer, an Opportunity or an Additional Threat?International journal of molecular sciences · 2026
    Review
  9. Article
  10. Article
  11. Ovarian Cancer Susceptibility and Chemosensitivity to KRAS Modulation.International journal of molecular sciences · 2026
    Article
  12. Article
  13. Review
  14. Article
  15. KRAS Withdrawal in Cholangiocarcinoma Leads to Immune Infiltration and Tumor Regression.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Anabela FerreiraCentre of Molecular and Environmental Biology (CBMA), Department of Biology, Campus de Gualtar, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0002-1417-3418
Flávia PereiraCentre of Molecular and Environmental Biology (CBMA), Department of Biology, Campus de Gualtar, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0003-2608-6511
Celso ReisInstitute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0002-0286-6639
Maria José OliveiraInstitute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugal.ORCID 0000-0002-0724-0272
Maria João SousaCentre of Molecular and Environmental Biology (CBMA), Department of Biology, Campus de Gualtar, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0001-9424-4150
Ana PretoCentre of Molecular and Environmental Biology (CBMA), Department of Biology, Campus de Gualtar, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0002-7302-0630
Universidade do Porto · PTUniversity of Minho · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

KRAS, one of the RAS protein family members, plays an important role in autophagy and apoptosis, through the regulation of several downstream effectors. In cancer cells,

Indexed as

Phosphatidylinositol 3-KinasesProto-Oncogene Proteins p21(ras)ApoptosisAutophagyCell Line, TumorMutationTNF-Related Apoptosis-Inducing LigandPhosphatidylinositol 3-KinasesProto-Oncogene Proteins p21(ras)TNF-Related Apoptosis-Inducing Ligandapoptosisautophagycell death resistanceKRAS mutations

Identifiers

PMID35883626
PMCPMC9319879
OpenAlexW4285393971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.