Evidence map›Paper›PMID 35883610›Full record

ArticleCells2022

Oral Administration of

Sunny Li-Yun Chang, Yen-You Lin, Shan-Chi Liu, You-Shan Tsai, Shih-Wei Lin, Yen-Lien Chen, Chin-Chu Chen, Chih-Yuan Ko, Hsien-Te Chen, Wei-Cheng Chen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. FermentedInternational journal of medical sciences · 2026
    Article
  6. Review
  7. Health-promoting effects ofBiochemistry and biophysics reports · 2025
    Article
  8. Article
  9. Review
  10. International journal of medical sciences · 2025
    Article
  11. Review
  12. Article
  13. Review
  14. Effects ofVeterinary sciences · 2024
    Article
  15. Review
  16. Article
  17. Review
  18. Oral administration of live combinedFrontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Sunny Li-Yun ChangGraduate Institute of Biomedical Science, China Medical University, Taichung 404333, Taiwan.
Yen-You LinSchool of Medicine, China Medical University, Taichung 404333, Taiwan.ORCID 0000-0002-7636-1115
Shan-Chi LiuDepartment of Medical Education and Research, Beigang Hospital, China Medical University, Yunlin 651012, Taiwan.
You-Shan TsaiBiotech Research Institute, Grape King Bio Ltd., Taoyuan 325002, Taiwan.ORCID 0000-0002-9585-2219
Shih-Wei LinBiotech Research Institute, Grape King Bio Ltd., Taoyuan 325002, Taiwan.
Yen-Lien ChenBiotech Research Institute, Grape King Bio Ltd., Taoyuan 325002, Taiwan.
Chin-Chu ChenInstitute of Food Science and Technology, National Taiwan University, Taipei 106617, Taiwan.
Chih-Yuan KoGraduate Institute of Biomedical Science, China Medical University, Taichung 404333, Taiwan.ORCID 0000-0001-7752-2833
Hsien-Te ChenDepartment of Orthopedic Surgery, China Medical University Hospital, Taichung 404333, Taiwan.
Wei-Cheng ChenDepartment of Medicine, MacKay Medical College, New Taipei 25245, Taiwan.
Chih-Hsin TangGraduate Institute of Biomedical Science, China Medical University, Taichung 404333, Taiwan.ORCID 0000-0002-7113-8352
China Medical University · TWGrape King (Taiwan) · TWAsia University · TWMackay Memorial Hospital · TWShih Chien University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoarthritis (OA) is a degenerative and painful inflammatory joint disease affecting the cartilage, bone, and synovial membranes, without any effective treatment that targets the underlying mechanisms of OA. Our study evaluated the therapeutic effects of a live probiotic strain,

Indexed as

Cartilage, ArticularClostridium butyricumOsteoarthritis, KneeAdministration, OralAnimalsRatsX-Ray Microtomographyanterior cruciate ligament transectionClostridium butyricum GKB7interleukin 1 betain vivoosteoarthritistumor necrosis factor alpha

Identifiers

PMID35883610
PMCPMC9323988
OpenAlexW4285033719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.