Yeast Kinesin-5 Motor Protein CIN8 Promotes Accurate Chromosome Segregation.

Delaney Sherwin, Abigail Huetteman, Yanchang Wang

Open access · goldAbstract read

In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.5field-weighted citation impact, top 43% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

A new layer of regulation of chromosomal passenger complex (CPC) translocation in budding yeast.Molecular biology of the cell · 2023
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Delaney SherwinDepartment of Biomedical Sciences, College of Medicine, Florida State University, 1115 West Call Street, Tallahassee, FL 32306-4300, USA.

Abigail HuettemanMedical Student, College of Medicine, Florida State University, 1115 West Call Street, Tallahassee, FL 32306-4300, USA.ORCID 0000-0002-9123-2143

Yanchang WangDepartment of Biomedical Sciences, College of Medicine, Florida State University, 1115 West Call Street, Tallahassee, FL 32306-4300, USA.

Florida State University · US

Funding

The Initiation of DNA Replication in EukaryotesR01GM121786 · NIGMS · FLORIDA STATE UNIVERSITY · PI WANG, YANCHANG · 2017 to 2020

$1.2M

NIGMS NIH HHS R01 GM121786

6 · The paper itself

Abstract

Accurate chromosome segregation depends on bipolar chromosome-microtubule attachment and tension generation on chromosomes. Incorrect chromosome attachment results in chromosome missegregation, which contributes to genome instability. The kinetochore is a protein complex that localizes at the centromere region of a chromosome and mediates chromosome-microtubule interaction. Incorrect chromosome attachment leads to checkpoint activation to prevent anaphase onset. Kinetochore detachment activates the spindle assembly checkpoint (SAC), while tensionless kinetochore attachment relies on both the SAC and tension checkpoint. In budding yeast

Indexed as

KinesinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsChromosome SegregationDyneinsIndoleacetic AcidsKinetochoresCIN8 protein, S cerevisiaeDyneinsIndoleacetic AcidsKinesinsSaccharomyces cerevisiae ProteinsCin8kinesin-5 motor proteinsKip1tension checkpointtension on chromosomes

Identifiers

PMID35883587

DOI10.3390/cells11142144

PMCPMC9316075

OpenAlexW4284899851

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.