ArticleBiomolecules2022
Transcriptomic and Metabolomic Analysis of the Response of Quinoa Seedlings to Low Temperatures.
Article in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Melatonin and Brassinolide Enhance Cold Tolerance inPlants (Basel, Switzerland) · 2026Article
- Advances in Proteomics and Functional Foods from Fermentation and Bioencapsulation of Andean Grains and Tubers: Applications and Perspectives.Foods (Basel, Switzerland) · 2026Review
- Identification and functional validation of hub genes responding to waterlogging stress during the filling period in quinoa (Chenopodium Quinoa Willd.).BMC plant biology · 2026Article
- Dynamic transcriptomic and metabolomic adaptation mechanisms of Trifolium ambiguum under different durations of cold stress.Scientific reports · 2025Article
- Screening of qPCR Reference Genes in Quinoa Under Cold, Heat, and Drought Gradient Stress.Plants (Basel, Switzerland) · 2025Article
- Article
- Quinoa-Peanut Relay Intercropping Promotes Peanut Productivity Through the Temporal Optimization of Soil Physicochemical Properties and Microbial Community Composition in Saline Soil.Plants (Basel, Switzerland) · 2025Article
- Physiological and broadly targeted metabolomic analyses of barley (Hordeum vulgare L.) in response to low-temperature stress.BMC genomics · 2025Article
- Comparative metabolomics of two nettle species unveils distinct high-altitude adaptation mechanisms on the Tibetan Plateau.BMC plant biology · 2025Article
- Comparative Transcriptomic Analyses Reveal Key Pathways in Response to Cold Stress at the Germination Stage of Quinoa (Plants (Basel, Switzerland) · 2025Article
- Genome-wide identification of the AAT gene family in quinoa and analysis of its expression pattern under abiotic stresses.BMC genomics · 2025Article
- Cold stress adaptation inFrontiers in plant science · 2025Article
- Comparative transcriptomes and WGCNA reveal hub genes for spike germination in different quinoa lines.BMC genomics · 2024Article
- Single-cell transcriptomic analysis reveals the developmental trajectory and transcriptional regulatory networks of quinoa salt bladders.Stress biology · 2024Article
- Flavonoid Synthesis Pathway Response to Low-Temperature Stress in a Desert Medicinal Plant,Genes · 2024Article
- Identifying Core Genes Related to Low-Temperature Stress Resistance in Quinoa Seedlings Based on WGCNA.International journal of molecular sciences · 2024Article
- Metabolomics-based exploration the response mechanisms of Saussurea involucrata leaves under different levels of low temperature stress.BMC genomics · 2023Article
- Nutritional Evaluation of Quinoa Genetic Resources Growing in the Climatic Conditions of Central Europe.Foods (Basel, Switzerland) · 2023Article
- Transcriptomic and metabolomic insights on the molecular mechanisms of flower buds in responses to cold stress in twoFrontiers in plant science · 2023Article
- Non-targeted metabolomics analysis reveals the mechanism of arbuscular mycorrhizal symbiosis regulating the cold-resistance ofFrontiers in microbiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Quinoa, a cool-weather high-altitude crop, is susceptible to low-temperature stress throughout its reproductive phase. Herein, we performed broadly targeted metabolic profiling of quinoa seedlings to explore the metabolites' dynamics in response to low-temperature stress and transcriptome analysis to determine the underlying genetic mechanisms. Two variants, namely, Dian Quinoa 2324 and Dian Quinoa 281, were exposed to temperatures of -2, 5, and 22 °C. A total of 794 metabolites were detected; 52,845 genes, including 6628 novel genes, were annotated using UPLC-MS/MS analysis and the Illumina HiSeq system. Combined with morphological indicators to resolve the mechanism underlying quinoa seedling response to low-temperature stress, the molecular mechanisms of quinoa changed considerably based on temperature exposure. Soluble sugars heavily accumulated in plants with cold damage and changes in regulatory networks under freeze damage, such as the upregulation of α-linolenic acid metabolism and a reduction in energy substrates, may explain the spatial patterns of biosynthesis and accumulation of these metabolites. Genes that are actively expressed during cold responses, as revealed by co-expression analyses, may be involved in the regulation thereof. These results provide insights into the metabolic factors in quinoa under low-temperature stress and provide a reference for the screening of quinoa varieties resistant to low temperature.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.