Evidence map›Paper›PMID 35883508›Full record

ReviewBiomolecules2022

Advances in MUC1-Mediated Breast Cancer Immunotherapy.

Zhifeng Li, Dazhuang Yang, Ting Guo, Mei Lin

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Knockout of Mucin 1 inhibits the proliferation, migration, and invasion of human MDA-MB-231 cells by blocking autophagy flow.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. New Radiopharmaceutical Tracers in Breast Cancer Diagnosis and Therapy.Anti-cancer agents in medicinal chemistry · 2025
    Review
  9. Article
  10. Article
  11. Tumor Antigens beyond the Human Exome.International journal of molecular sciences · 2024
    Review
  12. Review
  13. Article
  14. The Therapeutic Effects of MUC1-C shRNA@FeInternational journal of nanomedicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zhifeng LiMedical School of Nantong University, Nantong 226019, China.ORCID 0000-0002-6141-5184
Dazhuang YangMedical School of Nantong University, Nantong 226019, China.ORCID 0000-0001-9583-1007
Ting GuoResearch Center of Clinical Medicine, Jiangsu Taizhou People's Hospital (Affiliated Hospital 5 of Nantong University), Taizhou 225300, China.ORCID 0000-0002-3794-9346
Mei LinResearch Center of Clinical Medicine, Jiangsu Taizhou People's Hospital (Affiliated Hospital 5 of Nantong University), Taizhou 225300, China.
Nantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer (BRCA) is the leading cause of death from malignant tumors among women. Fortunately, however, immunotherapy has recently become a prospective BRCA treatment with encouraging achievements and mild safety profiles. Since the overexpression and aberrant glycosylation of MUC1 (human mucin) are closely associated with BRCA, it has become an ideal target for BRCA immunotherapies. In this review, the structure and function of MUC1 are briefly introduced, and the main research achievements in different kinds of MUC1-mediated BRCA immunotherapy are highlighted, from the laboratory to the clinic. Afterward, the future directions of MUC1-mediated BRCA immunotherapy are predicted, addressing, for example, urgent issues in regard to how efficient immunotherapeutic strategies can be generated.

Indexed as

Breast NeoplasmsFemaleGlycosylationHumansImmunologic FactorsImmunotherapyMucin-1MucinsProspective StudiesImmunologic FactorsMUC1 protein, humanMucin-1Mucinsbreast cancerimmunotherapyMUC1mucintarget

Identifiers

PMID35883508
PMCPMC9313386
OpenAlexW4283828519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.