ArticleAnimals : an open access journal from MDPI2022
Effect of Vaccination against
Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- FiveMicroorganisms · 2025Article
- Presence of Vaccine-Induced Antibodies AgainstVaccines · 2025Article
- Vaccination-Challenge Trials in Beagle Dogs Using Whole-CellPathogens (Basel, Switzerland) · 2025Article
- Seroprevalence and Molecular Epidemiology ofTransboundary and emerging diseases · 2025Article
- Diagnostic Pathways ofPathogens (Basel, Switzerland) · 2024Article
- Review of leptospirosis in dogs from Mexico: Epidemiology, diagnosis, prevention, and treatment.Veterinary world · 2024Review
- Canine leptospirosis: A One Health approach for improved surveillance, prevention, and interdisciplinary collaboration.The Canadian veterinary journal = La revue veterinaire canadienne · 2024Article
- Molecular Epidemiology of PathogenicAnimals : an open access journal from MDPI · 2023Article
- Cats' and dogs' welfare: text mining and topics modeling analysis of the scientific literature.Frontiers in veterinary science · 2023Review
- Comparison of the PF07598-Encoded Virulence-Modifying Proteins ofTropical medicine and infectious disease · 2022Review
- Updated ACVIM consensus statement on leptospirosis in dogs.Journal of veterinary internal medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
(1) Background: Vaccination of dogs against leptospirosis is of paramount importance, as they ideally must provide not only long-term protection, but also against the renal carrier state of leptospires. This study assessed the post-vaccine humoral response against Leptospira in naturally exposed dogs and effects on renal carrier status. (2) Methods: A total of 118 dogs were studied for 365 days, separated into Group A (vaccinated, n = 94) and Group B (non-vaccinated, n = 24). Group A was subdivided into three groups: A1 with 32 dogs immunized with the vaccine #1; A2 by 32 dogs with #2; and A3 30 dogs with #3. Serology (MAT and IgG-ELISA) and urinary PCR were conducted. (3) Results: Seroreactivity increased at D15 post-vaccination and, regardless of vaccine brand, remained high up to D180, with antibody switch to IgG after D30. A total of 46.8% of animals from Group A were PCR-positive at least once, in contrast to 75% in Group B, regardless of vaccine brand (p < 0.05; OR: 0.3). (4) Conclusions: All commercial vaccines succeeded at eliciting a long-term IgG-based response and were partially effective at protecting against kidney infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.