Evidence map›Paper›PMID 35883333›Full record

ArticleAnimals : an open access journal from MDPI2022

Effects of Probiotics on Growth and Immunity of Piglets.

Ahmad Farid Nikmal Azizi, Ryoko Uemura, Mariko Omori, Masuo Sueyoshi, Masahiro Yasuda

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Effect ofAnimals : an open access journal from MDPI · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Characterization of the Effects of a Novel Probiotic onAnimals : an open access journal from MDPI · 2024
    Article
  9. Frontiers in veterinary science · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ahmad Farid Nikmal AziziGraduate School of Medicine and Veterinary Medicine, University of Miyazaki, Miyazaki 889-2192, Japan.
Ryoko UemuraLaboratory of Animal Health, Faculty of Agriculture, University of Miyazaki, Miyazaki 889-2192, Japan.
Mariko OmoriLaboratory of Animal Health, Faculty of Agriculture, University of Miyazaki, Miyazaki 889-2192, Japan.
Masuo SueyoshiGraduate School of Medicine and Veterinary Medicine, University of Miyazaki, Miyazaki 889-2192, Japan.ORCID 0000-0002-6331-4002
Masahiro YasudaGraduate School of Medicine and Veterinary Medicine, University of Miyazaki, Miyazaki 889-2192, Japan.ORCID 0000-0002-8384-8167

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growth promoting antibiotics are used in modern animal husbandry to promote growth and avoid infections. Negative effects of these antibiotics on human health are a big concern and they need to be replaced. Probiotics are expected to be a good replacement for growth promoting antibiotics. In this study, we evaluated effects of probiotics on growth and immune status of liver and secondary lymphoid organs of piglets. Body weights of probiotic-fed piglets were heavier than those of control piglets (p < 0.05) at days 30 and 45 of the experiment. Relative populations of CD4+ and IgM+ cells isolated from the liver were significantly increased (p < 0.05 and p < 0.01, respectively) in probiotic-fed piglets compared to control piglets. CD4+CD8+ T cells were significantly decreased (p < 0.05) in jejunal Peyer’s patches of treated piglets. Phagocytosis of MHC class II+ cells isolated from the liver of probiotic-fed piglets was significantly higher (p < 0.05) than that of control piglets. Phagocytosis of granulocytes isolated from the liver and peripheral blood of probiotic-fed piglets were also higher than those of control piglets. These results indicate excellent effects on growth and immune status of piglets. In conclusion, probiotics have beneficial effects on the growth and health of piglets and could be good replacement for growth promoting antibiotics.

Indexed as

immunitylymphocyte subsetsphagocytosispigletsprobiotics

Identifiers

PMID35883333
PMCPMC9312027

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.