Evidence map›Paper›PMID 35883062›Full record

ArticleBMC infectious diseases2022

SARS-CoV-2 in a tropical area of Colombia, a remarkable conversion of presymptomatic to symptomatic people impacts public health.

Caty Martínez, Héctor Serrano-Coll, Álvaro Faccini, Verónica Contreras, Ketty Galeano, Yesica Botero, Yonairo Herrera, Alejandra Garcia, Evelin Garay, Ricardo Rivero and 6 more

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Characteristics of Oral Adverse Effects following COVID-19 Vaccination and Similarities with Oral Symptoms in COVID-19 Patients: Taste and Saliva Secretory Disorders.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Caty MartínezUniversidad de Córdoba, Instituto de Investigaciones Biológicas del Trópico, Campus Berastegui, Córdoba, Montería, Colombia.
Héctor Serrano-CollUniversidad de Córdoba, Instituto de Investigaciones Biológicas del Trópico, Campus Berastegui, Córdoba, Montería, Colombia.
Álvaro FacciniUniversidad de Córdoba, Instituto de Investigaciones Biológicas del Trópico, Campus Berastegui, Córdoba, Montería, Colombia.
Verónica ContrerasUniversidad de Córdoba, Instituto de Investigaciones Biológicas del Trópico, Campus Berastegui, Córdoba, Montería, Colombia.
Ketty GaleanoUniversidad de Córdoba, Instituto de Investigaciones Biológicas del Trópico, Campus Berastegui, Córdoba, Montería, Colombia.
Yesica BoteroUniversidad de Córdoba, Instituto de Investigaciones Biológicas del Trópico, Campus Berastegui, Córdoba, Montería, Colombia.
Yonairo HerreraUniversidad de Córdoba, Instituto de Investigaciones Biológicas del Trópico, Campus Berastegui, Córdoba, Montería, Colombia.
Alejandra GarciaUniversidad de Córdoba, Instituto de Investigaciones Biológicas del Trópico, Campus Berastegui, Córdoba, Montería, Colombia.
Evelin GarayUniversidad de Córdoba, Instituto de Investigaciones Biológicas del Trópico, Campus Berastegui, Córdoba, Montería, Colombia.
Ricardo RiveroUniversidad de Córdoba, Instituto de Investigaciones Biológicas del Trópico, Campus Berastegui, Córdoba, Montería, Colombia.
Héctor ContrerasUniversidad de Córdoba, Instituto de Investigaciones Biológicas del Trópico, Campus Berastegui, Córdoba, Montería, Colombia.
Yesica LópezUniversidad de Córdoba, Instituto de Investigaciones Biológicas del Trópico, Campus Berastegui, Córdoba, Montería, Colombia.
Camilo GuzmánUniversidad de Córdoba, Instituto de Investigaciones Biológicas del Trópico, Campus Berastegui, Córdoba, Montería, Colombia.
Jorge MirandaUniversidad de Córdoba, Instituto de Investigaciones Biológicas del Trópico, Campus Berastegui, Córdoba, Montería, Colombia.
Germán ArrietaUniversidad de Córdoba, Instituto de Investigaciones Biológicas del Trópico, Campus Berastegui, Córdoba, Montería, Colombia.
Salim MattarUniversidad de Córdoba, Instituto de Investigaciones Biológicas del Trópico, Campus Berastegui, Córdoba, Montería, Colombia. mattarsalim@hotmail.com.ORCID http://orcid.org/0000-0003-0526-4630
University of Córdoba · CO

Funding

Ministerio de Ciencia Tecnología e Innovación BPIN Code: 20200000100090
6 · The paper itself

Abstract

backgroundThe ability of SARS-CoV-2 to remain in asymptomatic individuals facilitates its dissemination and makes its control difficult.

objectiveTo establish a cohort of asymptomatic individuals, change to the symptomatic status, and determine the most frequent clinical manifestations. 

methodsBetween April 9 and August 9, 2020, molecular diagnosis of SARS-CoV-2 infection was confirmed in 154 asymptomatic people in contact with subjects diagnosed with COVID-19. Nasopharyngeal swabs were performed on these people in different hospitals in Córdoba, the Caribbean area of Colombia. The genes E, RdRp, and N were amplified with RT-qPCR. Based on the molecular results and the Cq values, the patients were subsequently followed up through telephone calls to verify their health conditions.

resultsOverall, of 154 asymptomatic individuals, 103 (66.9%) remained asymptomatic, and 51 (33.1%) changed to symptomatic. The most frequent clinical manifestations in young people were anosmia and arthralgia. Adults showed cough, ageusia, and odynophagia; in the elderly were epigastralgia, dyspnea, and headache. Mortality was 8%.

conclusionsA proportion of 33% of presymptomatic individuals was found, of which four of them died. This high rate could indicate a silent transmission, contributing significantly to the epidemic associated with SARS-CoV-2.

Indexed as

COVID-19SARS-CoV-2AdolescentAdultAgedColombiaCoughHumansPublic HealthConfounding factors epidemiologyDisease transmissionInfectiousPresymptomatic diseasePreventive measuresPreventive medicine and public health

Identifiers

PMID35883062
PMCPMC9321267
OpenAlexW4288053888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.