Evidence map›Paper›PMID 35883036›Full record

ArticleBMC public health2022

Factors associated with loss to follow up among HIV-exposed children: a historical cohort study from 2000 to 2017, in Porto Alegre, Brazil.

Karen da Silva Calvo, Daniela Riva Knauth, Bruna Hentges, Andrea Fachel Leal, Mariana Alberto da Silva, Danielle Lodi Silva, Samantha Correa Vasques, Letícia Hamester, Daila Alena Raenck da Silva, Fernanda Vaz Dorneles and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Adverse Perinatal Outcomes among Adolescent Pregnant Women Living with HIV: A Propensity-Score-Matched Study.International journal of environmental research and public health · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Karen da Silva CalvoGraduate Studies Program in Public Health, Federal University of Rio Grande Do Sul, Porto Alegre, RS, 90620-110, Brazil.
Daniela Riva KnauthDepartment of Social Medicine, Federal University of Rio Grande Do Sul, Porto Alegre, RS, Brazil.
Bruna HentgesDepartment of Social Medicine, Federal University of Rio Grande Do Sul, Porto Alegre, RS, Brazil.
Andrea Fachel LealGraduate Studies Program in Public Policy, Federal University of Rio Grande Do Sul, Porto Alegre, RS, Brazil.
Mariana Alberto da SilvaGraduate Studies Program in Public Health, Federal University of Rio Grande Do Sul, Porto Alegre, RS, 90620-110, Brazil.
Danielle Lodi SilvaGraduate Studies Program in Epidemiology, Federal University of Rio Grande Do Sul, Porto Alegre, RS, Brazil.
Samantha Correa VasquesGraduate Studies Program in Public Health, Federal University of Rio Grande Do Sul, Porto Alegre, RS, 90620-110, Brazil.
Letícia HamesterProfessional Master's in Family Health, Federal University of Rio Grande Do Sul, Porto Alegre, RS, Brazil.
Daila Alena Raenck da SilvaSchool of Nursing, Federal University of Rio Grande Do Sul, Porto Alegre, RS, Brazil.
Fernanda Vaz DornelesGeneral Directorate of Health Surveillance, Porto Alegre, RS, Brazil.
Fernando Santana FragaSchool of Nursing, Federal University of Rio Grande Do Sul, Porto Alegre, RS, Brazil.
Paulo Ricardo BobekGraduate Studies Program in Public Health, Federal University of Rio Grande Do Sul, Porto Alegre, RS, 90620-110, Brazil.
Luciana Barcellos TeixeiraGraduate Studies Program in Public Health, Federal University of Rio Grande Do Sul, Porto Alegre, RS, 90620-110, Brazil. Luciana.bteixeira@gmail.com.
Universidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are many inequalities in terms of prevention and treatment for pregnant women with HIV and exposed children in low and middle-income countries. The Brazilian protocol for prenatal care includes rapid diagnostic testing for HIV, compulsory notification, and monitoring by the epidemiological surveillance of children exposed to HIV until 18 months after delivery. The case is closed after HIV serology results are obtained. Lost to follow-up is defined as a child who was not located at the end of the case, and, therefore, did not have a laboratory diagnosis. Lost to follow-up is a current problem and has been documented in other countries. This study analyzed factors associated with loss to follow-up among HIV-exposed children, including sociodemographic, behavioral, and health variables of mothers of children lost to follow-up.

methodsThis historical cohort study included information on mothers of children exposed to HIV, born in Porto Alegre, from 2000 to 2017. The research outcome was the classification at the end of the child's follow-up (lost to follow-up or not). Factors associated with loss to follow-up were investigated using the Poisson regression model. Relative Risk calculations were performed. The significance level of 5% was adopted for variables in the adjusted model.

resultsOf 6,836 children exposed to HIV, 1,763 (25.8%) were classified as lost to follow-up. The factors associated were: maternal age of up to 22 years (aRR 1.25, 95% CI: 1.09-1.43), the mother's self-declared race/color being black or mixed (aRR 1.13, 95% CI: 1.03-1.25), up to three years of schooling (aRR 1.45, 95% CI: 1.26-1.67), between four and seven years of schooling (aRR 1.14, 95% CI: 1.02-1.28), intravenous drug use (aRR 1.29, 95% CI: 1.12-1.50), and HIV diagnosis during prenatal care or at delivery (aRR 1.37, 95% CI: 1.24-1.52).

conclusionVariables related to individual vulnerability, such as race, age, schooling, and variables related to social and programmatic vulnerability, remain central to reducing loss to follow-up among HIV-exposed children.

Indexed as

HIV InfectionsPregnancy Complications, InfectiousBrazilChildCohort StudiesFemaleFollow-Up StudiesHumansInfectious Disease Transmission, VerticalPregnancyChildren exposed to HIVHIV/AIDSLost to follow-upMother-to-child transmission of HIV

Identifiers

PMID35883036
PMCPMC9327199
OpenAlexW4288053899

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.