Evidence map›Paper›PMID 35883035›Full record

ArticleBMC gastroenterology2022

Endoscopic variceal obturation and retrograde transvenous obliteration for acute gastric cardiofundal variceal bleeding in liver cirrhosis.

Han Ah Lee, Jungwon Kwak, Sung Bum Cho, Young-Sun Lee, Young Kul Jung, Ji Hoon Kim, Seung Up Kim, Hyonggin An, Hyung Joon Yim, Jong Eun Yeon and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Han Ah Lee *Departments of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea.
Jungwon Kwak *Department of Radiology, Korea University College of Medicine, Seoul, Korea.
Sung Bum ChoDepartment of Radiology, Korea University College of Medicine, Seoul, Korea.
Young-Sun LeeDepartment of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Young Kul JungDepartment of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Ji Hoon KimDepartment of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Seung Up KimDepartment of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. KSUKOREA@yuhs.ac.ORCID http://orcid.org/0000-0002-9658-8050
Hyonggin AnDepartment of Biostatistics, Korea University College of Medicine, Seoul, Korea.
Hyung Joon YimDepartment of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Jong Eun YeonDepartment of Internal Medicine, Korea University College of Medicine, Seoul, Korea.
Yeon Seok SeoDepartment of Internal Medicine, Korea University College of Medicine, Seoul, Korea. drseo@korea.ac.kr.ORCID http://orcid.org/0000-0003-4171-6331
Korea University · KREwha Womans University · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsWe retrospectively compared the effect of endoscopic variceal obturation (EVO) and retrograde transvenous obliteration (RTO) in acute cardiofundal variceal bleeding.

methodsPatients with acute cardiofundal variceal bleeding treated with EVO or RTO at two hospitals were included.

resultsNinety patients treated with EVO and 86 treated with RTO were analyzed. The mean model for end-stage liver disease score was significantly higher in EVO group than in RTO group (13.5 vs. 11.7, P = 0.016). The bleeding control rates were high (97.8% vs. 96.5%), and the treatment-related complication rates were low in both EVO and RTO groups (2.2% vs. 3.5%). During the median follow-up of 18.0 months, gastric variceal (GV) and esophageal variceal rebleeding occurred in 34 (19.3%) and 7 (4.0%) patients, respectively. The all-variceal rebleeding rates were comparable between EVO and RTO groups (32.4% vs. 20.8% at 2-year, P = 0.150), while the GV rebleeding rate was significantly higher in EVO group than in RTO group (32.4% vs. 12.8% at 2-year, P = 0.003). On propensity score-matched analysis (71 patients in EVO vs. 71 patients in RTO group), both all-variceal and GV rebleeding rates were significantly higher in EVO group than in RTO group (all P < 0.05). In Cox regression analysis, EVO (vs. RTO) was the only significant predictor of higher GV rebleeding risk (hazard ratio 3.132, P = 0.005). The mortality rates were similar between two groups (P = 0.597).

conclusionsBoth EVO and RTO effectively controlled acute cardiofundal variceal bleeding. RTO was superior to EVO in preventing all-variceal and GV rebleeding after treatment, with similar survival outcomes.

Indexed as

Balloon OcclusionEnd Stage Liver DiseaseEsophageal and Gastric VaricesGastrointestinal HemorrhageHumansLiver CirrhosisRetrospective StudiesSeverity of Illness IndexTreatment OutcomeBalloon-occluded retrograde transvenous obliterationPortal hypertensionPreventionRebleedingVascular plug-assisted retrograde transvenous obliteration

Identifiers

PMID35883035
PMCPMC9317208
OpenAlexW4287877479

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.