Evidence map›Paper›PMID 35882933›Full record

ArticleNature immunology2022

Runx3 drives a CD8

Raíssa Fonseca, Thomas N Burn, Luke C Gandolfo, Sapna Devi, Simone L Park, Andreas Obers, Maximilien Evrard, Susan N Christo, Frank A Buquicchio, Caleb A Lareau and 10 more

Abstract read
In one paragraph

Article in Nature immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 115 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. AARS1-Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  5. Article
  6. Review
  7. CD8MedComm · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Contextualizing TNature reviews. Immunology · 2026
    Review
  15. Article
  16. Article
  17. Cancer Stem Cells Shift Metabolite Acetyl-Coenzyme A to Abrogate the Differentiation of CD103Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  18. Article
  19. Article
  20. Evolving role of CD8Frontiers in immunology · 2026
    Review

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 3 countries.

Raíssa Fonseca *Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Thomas N Burn *Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Luke C GandolfoDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID 0000-0002-3599-2455
Sapna DeviDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Simone L ParkDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Andreas ObersDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Maximilien EvrardDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID 0000-0002-2105-1160
Susan N ChristoDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Frank A BuquicchioDepartment of Pathology, Stanford University, Stanford, CA, USA.
Caleb A LareauDepartment of Pathology, Stanford University, Stanford, CA, USA.ORCID 0000-0003-4179-4807
Keely M McDonaldDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Sarah K SandfordDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID 0000-0002-2901-4516
Natasha M ZamudioDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Nagela G ZanluquiDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Ali ZaidMenzies Health Institute Queensland, Griffith University, Gold Coast Campus, Southport, Queensland, Australia.ORCID 0000-0002-2528-2783
Terence P SpeedSchool of Mathematics and Statistics, The University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0002-5403-7998
Ansuman T SatpathyDepartment of Pathology, Stanford University, Stanford, CA, USA.ORCID 0000-0002-5167-537X
Scott N MuellerDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.ORCID 0000-0002-3838-3989
Francis R CarboneDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.
Laura K MackayDepartment of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia. lkmackay@unimelb.edu.au.ORCID 0000-0002-8496-6632
The University of Melbourne · AUStanford University · USGladstone Institutes · USGriffith University · AU

Funding

Single-cell Mapping Center for Human Regulatory Elements and Gene ActivityUM1HG012076 · NHGRI · STANFORD UNIVERSITY · PI Michael Ryan Corces, Ansuman Satpathy · 2021 to 2026
$13.8M
4DN Interrogation of T Cell Exhaustion in CancerU01CA260852 · NCI · STANFORD UNIVERSITY · PI SATPATHY, ANSUMAN · 2020 to 2024
$2.6M
Howard Hughes Medical InstituteNCI NIH HHS U01 CA260852NHGRI NIH HHS UM1 HG012076
6 · The paper itself

Abstract

Tissue-resident memory T cells (T

Indexed as

Immunologic MemoryCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesTransforming Growth Factor betaTransforming Growth Factor beta

Identifiers

PMID35882933
PMCPMC13045866
OpenAlexW4288068856

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.