ArticleCommunications biology2022
Hypnotic enhancement of slow-wave sleep increases sleep-associated hormone secretion and reduces sympathetic predominance in healthy humans.
Article in Communications biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 28 citations in OpenAlex.
- Effects of unsupervised campus HIIT on fitness and sleep in sedentary male students: a randomized controlled trial.BMC public health · 2026Trial
- Sleep and obesity-known interactions and open questions.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Review
- Exploring the sleep quality-creativity relationship: a moderated mediation analysis of positive emotions and psychological capital.BMC psychology · 2026Article
- Effect of a 90-Minute Nap at Different Times of the Day on Physical Performance, Psycho-Cognitive Responses, and Perceived Recovery in Trained Youth Male Athletes.Sports (Basel, Switzerland) · 2025Article
- Leveraging transcranial ultrasound stimulation to enhance self-regulation in emotion and sleep.Frontiers in human neuroscience · 2025Article
- Sleep Architecture Changes in Diabetes.Journal of clinical medicine · 2024Review
- Slow-wave sleep and subsequent risk of dementia.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- Association of Disrupted Delta Wave Activity During Sleep With Long-Term Cardiovascular Disease and Mortality.Journal of the American College of Cardiology · 2024Article
- Interorgan rhythmicity as a feature of healthful metabolism.Cell metabolism · 2024Review
- From macro to micro: slow-wave sleep and its pivotal health implications.Frontiers in sleep · 2024Review
- The influence of experience and modality of presentation (online vs. offline) on hypnotizability.Frontiers in psychology · 2023Article
- The top 100 most cited papers in insomnia: A bibliometric analysis.Frontiers in psychiatry · 2022Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sleep is important for normal brain and body functioning, and for this, slow-wave sleep (SWS), the deepest stage of sleep, is assumed to be especially relevant. Previous studies employing methods to enhance SWS have focused on central nervous components of this sleep stage. However, SWS is also characterized by specific changes in the body periphery, which are essential mediators of the health-benefitting effects of sleep. Here we show that enhancing SWS in healthy humans using hypnotic suggestions profoundly affects the two major systems linking the brain with peripheral body functions, i.e., the endocrine and the autonomic nervous systems (ANS). Specifically, hypnotic suggestions presented at the beginning of a 90-min afternoon nap to promote subsequent SWS strongly increased the release of growth hormone (GH) and, to a lesser extent, of prolactin and aldosterone, and shifted the sympathovagal balance towards reduced sympathetic predominance. Thus, the hypnotic suggestions induced a whole-body pattern characteristic of natural SWS. Given that the affected parameters regulate fundamental physiological functions like metabolism, cardiovascular activity, and immunity, our findings open up a wide range of potential applications of hypnotic SWS enhancement, in addition to advancing our knowledge on the physiology of human SWS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.