Evidence map›Paper›PMID 35882773›Full record

ArticleInfection2023

Non-HIV-related comorbidities and uncontrolled HIV replication are independent factors increasing the odds of hospitalization due to COVID-19 among HIV-positive patients in Poland.

Justyna D Kowalska, Martyna Lara, Maria Hlebowicz, Elżbieta Mularska, Elżbieta Jabłonowska, Ewa Siwak, Alicja Wandałowicz, Magdalena Witak-Jędra, Anita Olczak, Monika Bociąga-Jasik and 4 more

Open access · greenAbstract read
In one paragraph

Article in Infection, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 1 country.

Justyna D KowalskaDepartment of Adults' Infectious Diseases, Medical University in Warsaw, Warsaw, Poland.ORCID http://orcid.org/0000-0003-1166-4462
Martyna Lara3rd Department, Hospital for Infectious Diseases in Warsaw, Warsaw, Poland. gomulskamartyna@gmail.com.
Maria HlebowiczDepartment of Infectious Diseases, Faculty of Medicine, Medical University of Gdansk, Gdańsk, Poland.
Elżbieta MularskaOutpatient Clinic for AIDS Diagnostics and Therapy Specialistic Hospital, Chorzow, Poland.
Elżbieta JabłonowskaDepartment of Infectious Diseases and Hepatology, Medical University of Lodz, Lodz, Poland.
Ewa SiwakHIV Out-Patient Clinic, Hospital for Infectious Diseases in Warsaw, Warsaw, Poland.
Alicja WandałowiczDepartment of Infectious Diseases and Hepatology, Medical University of Bialystok, Białystok, Poland.
Magdalena Witak-JędraDepartment of Infectious, Tropical Diseases and Immune Deficiency, Pomeranian Medical University in Szczecin, Szczecin, Poland.
Anita OlczakDepartment of Infectious Diseases and Hepatology, Nicolaus Copernicus University Collegium Medicum in Bydgoszcz, Bydgoszcz, Poland.
Monika Bociąga-JasikDepartment of Infectious and Tropical Diseases, Faculty of Medicine, Jagiellonian University Medical College, 30-688, Kraków, Poland.
Magdalena SuchaczDepartment of Infectious and Tropical Diseases and Hepatology, Medical University of Warsaw, Warsaw, Poland.
Justyna Stempkowska-RejekDepartment of Infectious Diseases, Medical University of Lublin, Lublin, Poland.
Piotr Wasilewski4Th Department, Hospital for Infectious Diseases in Warsaw, Warsaw, Poland.ORCID http://orcid.org/0000-0001-9301-7140
Miłosz ParczewskiDepartment of Infectious, Tropical Diseases and Immune Deficiency, Pomeranian Medical University in Szczecin, Szczecin, Poland.
Medical University of Warsaw · PLPomeranian Medical University · PLGdańsk Medical University · PLJagiellonian University · PLMedical University of Białystok · PLMedical University of Lodz · PLMedical University of Lublin · PLNicolaus Copernicus University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeImmunocompromised patients are postulated to be at elevated risk of unfavorable outcomes of COVID-19. The exact effect of HIV infection on the course of COVID-19 remains to be elucidated. The aim of the study was to describe the epidemiological and clinical aspects of SARS-CoV-2 infection in HIV-infected individuals.

methodsThe HIV-positive patients who were diagnosed with SARS-CoV-2 infection were identified through thirteen specialist HIV clinics routinely following them due to HIV treatment. The data were collected between November 2020 and May 2021 through an on-line electronical case report form (SurveyMonkey

resultsOne hundred and seventy-three patients with HIV-SARS-CoV-2 coinfection were included in the analysis. One hundred and sixty-one (93.1%) subjects had a symptomatic course of the disease. Thirty-nine (23.1%) of them were hospitalized, 23 (13.3%) necessitated oxygen therapy. Three (1.8%) patients required admission to the intensive care unit and 6 (3.5%) patients died. The presence of comorbidities and an HIV viral load of more than 50 copies/mL were linked to the increased odds of hospitalization (OR 3.24 [95% CI 1.27-8.28]) and OR 5.12 [95% CI 1.35-19.6], respectively).

conclusionsAs depicted by our analyses, HIV-positive patients with comorbidities and/or uncontrolled HIV replication who are diagnosed with SARS-CoV-2 infection should be considered of high risk of poor COVID-19 outcome and followed up carefully.

Indexed as

COVID-19HIV InfectionsHospitalizationHumansPolandSARS-CoV-2Virus ReplicationCOVID-19DeathHIVHospitalizationSARS-CoV-2

Identifiers

PMID35882773
PMCPMC9325668
OpenAlexW4288176564

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.