Evidence map›Paper›PMID 35882753›Full record

ArticleJournal of neuro-oncology2022

Revisitation of imaging features of skull base chondrosarcoma in comparison to chordoma.

Hirotaka Hasegawa, Masahiro Shin, Ryoko Niwa, Satoshi Koizumi, Shoko Yoshimoto, Naoyuki Shono, Yuki Shinya, Hirokazu Takami, Shota Tanaka, Motoyuki Umekawa and 3 more

Abstract read
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In one paragraph

Article in Journal of neuro-oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  4. Article
  5. Imaging of the skull base and orbital tumors.Japanese journal of radiology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Hirotaka HasegawaDepartment of Neurosurgery, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 1138655, Japan. hasegawah-nsu@h.u-tokyo.ac.jp.ORCID http://orcid.org/0000-0002-3585-2188
Masahiro ShinDepartment of Neurosurgery, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 1138655, Japan.
Ryoko NiwaDepartment of Neurosurgery, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 1138655, Japan.
Satoshi KoizumiDepartment of Neurosurgery, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 1138655, Japan.
Shoko YoshimotoDepartment of Neurosurgery, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 1138655, Japan.
Naoyuki ShonoDepartment of Neurosurgery, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 1138655, Japan.
Yuki ShinyaDepartment of Neurosurgery, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 1138655, Japan.
Hirokazu TakamiDepartment of Neurosurgery, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 1138655, Japan.
Shota TanakaDepartment of Neurosurgery, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 1138655, Japan.
Motoyuki UmekawaDepartment of Neurosurgery, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 1138655, Japan.
Shiori AmemiyaDepartment of Radiology, The University of Tokyo, Bunkyo, Tokyo, Japan.
Taichi KinDepartment of Neurosurgery, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 1138655, Japan.
Nobuhito SaitoDepartment of Neurosurgery, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 1138655, Japan.
The University of Tokyo · JPBunkyo University · JPUniversity of Tokyo Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePre-surgical diagnosis of skull base chondrosarcoma (SBC) is often challenging due to the resemblance to chordoma. The goal of this study was to develop an optimal method for predicting SBC diagnosis.

methodsThis retrospective study included patients with histologically diagnosed SBC and skull base chordoma. Their clinical and radiologic features were compared, and the predictive factors of SBC were examined.

resultsForty-one patients with SBC and 41 with chordoma were included. Most SBCs exhibited hypointensity (25, 64.1%) or isointensity (12, 30.8%) on T1-weighted images, and hyperintensity (34, 87.1%) or mixed intensity (5, 12.8%) on T2-weighted images. MRI contrast enhancement was usually avid or fair (89.7%) with "arabesque"-like pattern (41.0%). The lateral/paramidline location was more common in SBC than in chordoma (85.4% vs. 9.8%; P < 0.01), while midline SBCs (14.6%) were also possible. Multivariate analysis demonstrated that higher apparent diffusion coefficient (ADC) value (unit odds ratio 1.01; 95% confidence interval 1.00-1.02; P < 0.01) was associated with an SBC diagnosis. An ADC value of ≥ 1750 × 10

conclusionThe ADC-based method is helpful in distinguishing SBC from chordoma and readily applicable in clinical practice. The prediction accuracy increases when other characteristics of SBC, such as non-midline location and arabesque-like enhancement, are considered together.

Indexed as

ChondrosarcomaChordomaSkull Base NeoplasmsHumansMagnetic Resonance ImagingRetrospective StudiesSkull BaseApparent diffusion coefficientChondrosarcomaChordomaDifferential diagnosisMagnetic resonance imagingRadiologic featuresSkull base

Identifiers

PMID35882753
OpenAlexW4288077882

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.