ReviewApplied microbiology and biotechnology2022
Gut microbiome and aging nexus and underlying mechanism.
Review in Applied microbiology and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Age-Related Cognitive Decline, Focus on Microbiome: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2023Pooled it
- Geographical diet variations and microbial diversity: insights into François' langur's adaptive strategies.mSphere · 2026Article
- Identification of fecal microbiome signatures associated with longevity through 16S rRNA sequencing in different age groups in China.Applied microbiology and biotechnology · 2026Article
- The gut-skin axis in melanoma: from microbial regulatory mechanisms to clinical translation for precision management.Frontiers in microbiology · 2026Review
- Article
- Research on the characteristics of gut microbiota in overweight patients with early-onset type 2 diabetes mellitus.Journal of diabetes investigation · 2025Article
- Nutraceuticals in the Management of Intestinal Inflammation-Current Advances and Future Challenges.Nutrients · 2025Article
- Microbiome Research in Greece: A Comprehensive Bibliometric Study.Microorganisms · 2025Article
- Achieving healthy aging through gut microbiota-directed dietary intervention: Focusing on microbial biomarkers and host mechanisms.Journal of advanced research · 2025Review
- The Effects of DietaryAnimals : an open access journal from MDPI · 2024Article
- Structural characteristics of gut microbiota in longevity from Changshou town, Hubei, China.Applied microbiology and biotechnology · 2024Article
- Selenium- and/or Zinc-Enriched Egg Diet Improves Oxidative Damage and Regulates Gut Microbiota in D-Gal-Induced Aging Mice.Nutrients · 2024Article
- Gut microbiota: an ideal biomarker and intervention strategy for aging.Microbiome research reports · 2024Review
- Differential analysis of serum immunology and gut microbiota in patients with gastrointestinal diseases.Frontiers in microbiology · 2024Article
- Changes in Gut Microbiota Associated with Parity in Large White Sows.Animals : an open access journal from MDPI · 2023Article
- Uterine microbial communities and their potential role in the regulation of epithelium cell cycle and apoptosis in aged hens.Microbiome · 2023Article
- High-Throughput Sequencing Reveals a Dynamic Bacterial Linkage between the Captive White Rhinoceros and Its Environment.Microbiology spectrum · 2023Article
- Gut microbiota enhance energy accumulation of black-necked crane to cope with impending migration.Applied microbiology and biotechnology · 2023Article
- Physical Activity and Diet in Older Women: A Narrative Review.Journal of clinical medicine · 2022Review
- Association between Microbiome-Related Human Genetic Variants and Fasting Plasma Glucose in a High-Cardiovascular-Risk Mediterranean Population.Medicina (Kaunas, Lithuania) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
According to the United Nations population profile, the number of individuals aged 60 and over in high-income nations is expected to rise from 302 million to over 366 million between 2019 and 2030, so there is an increasing emphasis on nutrition and health in older people. Numerous studies have demonstrated the crucial role that gut microbiota plays in maintaining human health. As a model of healthy aging, centenarians have different gut microbiota from ordinary elderly people. The core microbiome of centenarians in various countries has shown some common characteristics, which are worth further exploration. In this review, the significance of the human gut microbiota to health is briefly discussed, and the characteristics of the gut microbiota of long-lived senior persons of different ages and in different countries are described. Moreover, this review lists dietary interventions and fecal microbiota transplantation. In the end, it discusses the pros and cons of using probiotics to enhance the health of seniors through focused management of the gut microbiota. It aims to pave the way for further investigation into the nexus between gut microbiota, probiotics, and longevity, and then to reveal the underlying mechanism to promote longevity. KEY POINTS: • Gut microbial structure in different age groups and the characteristics of gut microbiota in centenarians. • Dietary interventions, fecal transplants, and probiotics target the modulation of gut microbiota for healthy aging.
Indexed as
Identifiers
35882675What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.