ArticleJournal of neurointerventional surgery2023
CLinical Assessment of WEB device in Ruptured aneurYSms (CLARYS): 12-month angiographic results of a multicenter study.
Article in Journal of neurointerventional surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 3 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- European Stroke Organisation (ESO), European Association of Neurosurgical Societies (EANS) and European Society for Minimally Invasive Neurological Therapy (ESMINT) guideline on aneurysmal subarachnoid haemorrhage.European stroke journal · 2026Guideline
- Comparative outcomes of coil embolization and surgical clipping in elderly patients with subarachnoid hemorrhage: a systematic review and meta-analysis.Neurosurgical review · 2025Pooled it
- Retreatment rate and strategies for recurrent and residual aneurysms after Woven EndoBridge (WEB) treatment: a comprehensive systematic review and meta-analysis.Neurosurgical review · 2025Pooled it
- Early Aneurysm Occlusion Outcomes After Endovascular Treatment: A Descriptive Single-Center Cohort Evaluation.Neurology international · 2026Article
- Smaller WEB devices show lower retreatment rates than larger devices: results from the WorldWideWEB study.European radiology · 2026Article
- Catastrophic Rebleeding during Woven EndoBridge Treatment of a Large Ruptured Internal Carotid Artery Aneurysm with a Fetal-Type Posterior Communicating Artery: A Case Report.Neurointervention · 2026Article
- Woven Endobridge device for ruptured vs. unruptured aneurysms: insights from the WorldWideWEB study.Neuroradiology · 2026Article
- Device selection and clinical outcomes of adjunctive techniques for ruptured intracranial aneurysms: Insights from the JR-NET4 nationwide registry.Neuroradiology · 2026Article
- Safety and Efficacy of the Woven EndoBridge Device for Wide-Neck Bifurcation Intracranial Aneurysms: 1-Year Results of the W-EB DB Study.Journal of neuroendovascular therapy · 2026Article
- Stent-Assisted Coil Embolization for Ruptured Wide-Neck Aneurysms in the Acute Phase of Subarachnoid Hemorrhage: A Single-Center Experience in Japan.Journal of neuroendovascular therapy · 2026Article
- Balloon assisted Woven endobridge deployment (BAWD): A safety and efficacy study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- 15 years of WEB embolization: a transformative journey in aneurysm treatment.Journal of neurointerventional surgery · 2025Article
- Neck apposition is a key factor for aneurysm occlusion after Woven EndoBridge device embolization.Journal of neurointerventional surgery · 2025Article
- Microsurgical clipping of a recurrent anterior communicating artery aneurysm following WEB intrasaccular embolization: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Microsurgical clipping of ruptured wide-neck Aneurysms: A comparative analysis with Woven EndoBridge data.Brain & spine · 2025Article
- Intrasaccular Treatment of Intracranial Aneurysms: A Comprehensive Review.Journal of clinical medicine · 2024Review
- Flow Diversion for Endovascular Treatment of Intracranial Aneurysms: Past, Present, and Future Directions.Journal of clinical medicine · 2024Review
- Comparison of Angiographic Outcomes of Woven EndoBridge and Balloon-Assisted Coiling for the Treatment of Ruptured Wide-Necked Aneurysms: A Multicentric Study.Stroke (Hoboken, N.J.) · 2024Article
- Safety and effectiveness of the Woven EndoBridge (WEB) system for the treatment of wide necked bifurcation aneurysms: final 5 year results of the pivotal WEB Intra-saccular Therapy study (WEB-IT).Journal of neurointerventional surgery · 2023Article
- Lateral Compression is the Strongest Independent Predictor of Aneurysm Occlusion After Endovascular Treatment of Intracranial Aneurysms With the Woven EndoBridge Device.Neurosurgery practice · 2023Article
Corrections and comments
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Authors and funding
35 authors at 19 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe CLinical Assessment of WEB device in Ruptured aneurYSms (CLARYS) study has shown that the endovascular treatment of ruptured bifurcation aneurysms with the Woven EndoBridge (WEB) is safe and effective and provides protection against rebleeding at 1 month and 1 year. The 12-month angiographic follow-up is an important endpoint of the study.
methodsThe CLARYS study is a prospective multicenter study conducted in 13 European centers. The study enrolled 60 patients with 60 ruptured aneurysms of the anterior and posterior circulation. The study was conducted with an independent assessment of safety outcomes and imaging.
resultsSixty patients with 60 ruptured bifurcation aneurysms to be treated with the WEB were included. Fifty-three aneurysms (88.3%) had a broad base with a dome to neck ratio <2 (mean 1.6). Of these, 46 patients were evaluated by an independent core laboratory with follow-up imaging performed at 12 months or before eventual retreatment. At 1 year, 19/46 aneurysms (41.3%) were completely occluded (Raymond-Roy grade I), 21/46 (45.7%) had a residual neck and 6/46 (13.0%) had residual aneurysm filling. Adequate occlusion was reported in 40/46 (87%) aneurysms. Six patients underwent target aneurysm retreatment.
conclusionsThe CLARYS study has previously shown that the use of the WEB in the endovascular treatment of ruptured bifurcation aneurysms provides effective protection against rebleeding with a good safety profile. The angiographic occlusion rates at 1 year reported here are comparable to those already seen in previous multicenter studies which primarily included unruptured aneurysms.
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