Evidence map›Paper›PMID 35882451›Full record

Trial reportBMJ open2022

Safety, feasibility and initial efficacy of an app-facilitated telerehabilitation (AFTER) programme for COVID-19 survivors: a pilot randomised study.

Jacob John Capin, Sarah E Jolley, Mary Morrow, Meghan Connors, Kristine Hare, Samantha MaWhinney, Amy Nordon-Craft, Michelle Rauzi, Sheryl Flynn, Jennifer E Stevens-Lapsley and 1 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04663945 (Predictors of Recovery and the App-Facilitated Tele-Rehabilitation), which is not on this map. Cited by 37 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04663945 nacompletednot on this map

Predictors of Recovery and the App-Facilitated Tele-Rehabilitation (AFTER) Program for COVID Survivors

TypeinterventionalSponsorUniversity of Colorado, DenverRan2020 to 2021Enrolled49ConditionsCovid-19, DeconditioningArmsBiobehavioral Tele-rehabilitation Sessions
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Rehabilitation and COVID-19: systematic review by Cochrane Rehabilitation.European journal of physical and rehabilitation medicine · 2023
    Pooled it
  7. Pooled it
  8. Pooled it
  9. Trial
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  12. Pitavastatin Is Well-Tolerated With no Detrimental Effects on Physical Function.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025 · on this map
    Trial
  13. Trial
  14. Article
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  17. Review
  18. The Safety of Telerehabilitation: Systematic Review.JMIR rehabilitation and assistive technologies · 2025
    Review
  19. Observational
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jacob John CapinDepartment of Physical Medicine & Rehabilitation, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0001-9361-3700
Sarah E JolleyDivision of Pulmonary and Critical Care Medicine, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado, USA.
Mary MorrowDepartment of Biostatistics and Informatics, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado, USA.
Meghan ConnorsDepartment of Physical Medicine & Rehabilitation, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado, USA.
Kristine HareDepartment of Physical Medicine & Rehabilitation, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado, USA.
Samantha MaWhinneyDepartment of Biostatistics and Informatics, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado, USA.
Amy Nordon-CraftDepartment of Physical Medicine & Rehabilitation, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado, USA.
Michelle RauziDepartment of Physical Medicine & Rehabilitation, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado, USA.
Sheryl FlynnBlue Marble Health, Altadena, California, USA.
Jennifer E Stevens-LapsleyDepartment of Physical Medicine & Rehabilitation, University of Colorado Denver - Anschutz Medical Campus, Aurora, Colorado, USA.
Kristine M ErlandsonDivision of Infectious Diseases, University of Colorado - Anschutz Medical Campus, Aurora, Colorado, USA Kristine.erlandson@cuanschutz.edu.

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
University of Colorado Aging Training GrantT32AG000279 · NIA · UNIVERSITY OF COLORADO DENVER · PI Kerrie Moreau · 2001 to 2026
$10.1M
Predictors of Recovery and the App-Facilitated Tele-Rehabilitation (AFTER) Program for COVID SurvivorsR01AG054366 · NIA · UNIVERSITY OF COLORADO DENVER · PI ERLANDSON, KRISTINE MACE · 2016 to 2020
$3.4M
Prevalence of ICU-Acquired Myopathy in Patients with Alcohol Use DisordersK23AA026315 · NIAAA · UNIVERSITY OF COLORADO DENVER · PI JOLLEY, SARAH E · 2018 to 2022
$696k
Contralateral Knee Osteoarthritis Among Older Adults after Primary Total Knee ArthroplastyF32AG066274 · NIA · UNIVERSITY OF COLORADO DENVER · PI CAPIN, JACOB J · 2019 to 2021
$94k
NCATS NIH HHS UL1 TR002535NIAAA NIH HHS K23 AA026315NIA NIH HHS F32 AG066274NIA NIH HHS R01 AG054366NIA NIH HHS T32 AG000279
6 · The paper itself

Abstract

objectivesDetermine the safety, feasibility and initial efficacy of a multicomponent telerehabilitation programme for COVID-19 survivors.

designPilot randomised feasibility study.

settingIn-home telerehabilitation.

participants44 participants (21 female, mean age 52 years) discharged home following hospitalisation with COVID-19 (with and without intensive care unit (ICU) stay).

interventionsParticipants were block randomised 2:1 to receive 12 individual biobehaviourally informed, app-facilitated, multicomponent telerehabilitation sessions with a licenced physical therapist (n=29) or to a control group (n=15) consisting of education on exercise and COVID-19 recovery trajectory, physical activity and vitals monitoring, and weekly check-ins with study staff. Interventions were 100% remote and occurred over 12 weeks. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was feasibility, including safety and session adherence. Secondary outcomes included preliminary efficacy outcomes including tests of function and balance; patient-reported outcome measures; a cognitive assessment; and average daily step count. The 30 s chair stand test was the main secondary (efficacy) outcome.

resultsNo adverse events (AEs) occurred during testing or in telerehabilitation sessions; 38% (11/29) of the intervention group compared with 60% (9/15) of the control group experienced an AE (p=0.21), most of which were minor, over the course of the 12-week study. 27 of 29 participants (93%; 95% CI 77% to 99%) receiving the intervention attended ≥75% of sessions. Both groups demonstrated clinically meaningful improvement in secondary outcomes with no statistically significant differences between groups.

conclusionFully remote telerehabilitation was safe, feasible, had high adherence for COVID-19 recovery, and may apply to other medically complex patients including those with barriers to access care. This pilot study was designed to evaluate feasibility; further efficacy evaluation is needed. TRIAL REGISTRATION NUMBER: NCT04663945.

Indexed as

COVID-19Mobile ApplicationsTelerehabilitationFeasibility StudiesFemaleHumansMiddle AgedPilot ProjectsSurvivorsCOVID-19Rehabilitation medicineREHABILITATION MEDICINE

Identifiers

PMID35882451
PMCPMC9329728

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.