ReviewThe Journal of organic chemistry2023
Innovations and Inventions: Why Was the Ugi Reaction Discovered Only 37 Years after the Passerini Reaction?
Review in The Journal of organic chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed.
- Diastereoselective synthesis of tetrahydroisoquinolines through the Pd-catalyzed post-Ugi transformations.RSC advances · 2026Article
- Generating multimillion chemical space based on the Ugi four-center three-component reaction with oxocarboxylic acids.Molecular diversity · 2026Article
- One-pot three-component synthesis of azaspirononatriene derivatives.Scientific reports · 2025Article
- Navigating Unexplored Territories of the Interrupted Ugi and Passerini Reactions toward Peptidomimetics.Organic letters · 2025Article
- Silver(I) triflate-catalyzed post-Ugi synthesis of pyrazolodiazepines.Beilstein journal of organic chemistry · 2025Article
- Accessing Promising Passerini Adducts in Anticancer Drug Design.Molecules (Basel, Switzerland) · 2024Article
- Diversifying DNA-Tagged Amines by Isocyanide Multicomponent Reactions for DNA-Encoded Library Synthesis.ACS omega · 2024Article
- 100 years of isocyanide-based multicomponent reactions.Molecular diversity · 2024Article
- Crystal Clear: Decoding Isocyanide Intermolecular Interactions through Crystallography.The Journal of organic chemistry · 2024Article
- Multicomponent Reaction-Assisted Drug Discovery: A Time- and Cost-Effective Green Approach Speeding Up Identification and Optimization of Anticancer Drugs.International journal of molecular sciences · 2023Review
- Ugi Four-Component Reactions Using Alternative Reactants.Molecules (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This year represents the 100th anniversary of the discovery of the Passerini three-component reaction. The related Ugi four-compound reaction was discovered 37 years after the Passerini reaction. Undoubtedly, both reactions are very important multicomponent reactions but the Ugi reactions outperform the Passerini reactions in terms of combinatorial space according to the equation
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.